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Factors Associated with Hepatitis B Surface Antigen Among Pregnant Women Attending Ante-Natal Care Clinics at Misungwi, Sumve and Magu District Hospital, Mwanza, Tanzania.

By: Contributor(s): Material type: TextTextPublication details: Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] Phone: +255 28 298 3384 : Fax: +255 28 298 3386 : Email: vc@bugando.ac.tz : Website: www.bugando.ac.tz: © 2019Description: vii; 43 Pages; Includes Refferences and AppendicesSubject(s): Summary: Abstract: Background: Hepatitis B virus (HBV) infection is one of the most common public problems worldwide. Over one million people die annually of HBV-related chronic liver disease. HBV infection during pregnancy can lead to unpropitious consequences to the infant yet to be born. This study will determine the magnitude and associated factors of HBV in pregnant women. Also the results obtained can be used as the baseline information to ascent the gap for future research and insistence on the importance of vaccination of women of reproductive age. Methods: A cross-sectional hospital based conducted between May and July 2019 among pregnant women attending ante-natal clinic at districts hospitals (Magu, Sumve and Misungwi). Pre-tested structured questionnaires were used for collection of socio-demographic and clinical information. Venous blood specimens were collected from participants and then centrifuged to obtain sera. Sera was analyzed for Hepatitis B surface antigen (HBsAg) using One-step HBV rapid test (POCT, EGENS DIAGNOSTICS, China). STATA version 13.0 was used for data analysis. Results: A total of 300 pregnant women with median age of 25 (IQS: 21-30) years were enrolled their age ranged from 15 to 48 years. Among the 300 participants tested for HBV antigen, only 15(5%) tested positive for HBV antigen. History of traditional marks was found to statistically significant as a factor associated with HBV infection in pregnant women. Conclusion and Recommendation: This study found moderate prevalence (5%) of HBV infection among pregnant women attending ANC clinics in Mwanza district hospitals and history of traditional marks was statistically significant. We recommend screening transmission to unborn children.
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UNDERGRADUATE DISSERTATIONS MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO NFIC 1 UD0786
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Abstract:

Background: Hepatitis B virus (HBV) infection is one of the most common public problems worldwide. Over one million people die annually of HBV-related chronic liver disease. HBV infection during pregnancy can lead to unpropitious consequences to the infant yet to be born. This study will determine the magnitude and associated factors of HBV in pregnant women. Also the results obtained can be used as the baseline information to ascent the gap for future research and insistence on the importance of vaccination of women of reproductive age.

Methods: A cross-sectional hospital based conducted between May and July 2019 among pregnant women attending ante-natal clinic at districts hospitals (Magu, Sumve and Misungwi). Pre-tested structured questionnaires were used for collection of socio-demographic and clinical information. Venous blood specimens were collected from participants and then centrifuged to obtain sera. Sera was analyzed for Hepatitis B surface antigen (HBsAg) using One-step HBV rapid test (POCT, EGENS DIAGNOSTICS, China). STATA version 13.0 was used for data analysis.

Results: A total of 300 pregnant women with median age of 25 (IQS: 21-30) years were enrolled their age ranged from 15 to 48 years. Among the 300 participants tested for HBV antigen, only 15(5%) tested positive for HBV antigen. History of traditional marks was found to statistically significant as a factor associated with HBV infection in pregnant women.

Conclusion and Recommendation: This study found moderate prevalence (5%) of HBV infection among pregnant women attending ANC clinics in Mwanza district hospitals and history of traditional marks was statistically significant. We recommend screening transmission to unborn children.

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