In Vitro Antifungal Activities of Guava Leaf (Psidium Guajava L.) on Pathogenic Candida Albicans in Mwanza Tanzania.
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TextPublisher number: Wurzburg Road 35, BMC Premises, Post Code: 33102: P. O. Box 1464, Mwanza – Tanzania: Phone: +255 28 298 3384: Fax: +255 28 298 3386: Email: vc@bugando.ac.tz:www.bugando.ac.tzLanguage: English Language: Kiswahili Publication details: Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] : ©2017Description: viii; 19 Pages; Includes ReferencesSubject(s): Summary: Abstract:
Background: Guava leaves [psidium quajava Linn.] Myrtaceae. The plant is originated from Mexco spread throughout America. Europe, Africa and Asia. The tree of guava grows in the tropical and subtropical areas of the world in the different climatic conditions. Guava leaves are found in a small three which is 10m high with thin smooth patch, pealing bark. Leaves are opposite with short petiolate and has oval blade with prominent veins 5-15 cm long. (1) Guava leaf is reported that a green immature leaves contains sterols, tannins, proteins and aminoacids. However ever tannins investigated to have inhibitory activity in five different pathogens microbial like Escherichia Coli, Pseudomonas aurreginose, Staphylococcus aureas, Aspergillus niger and Candida albicans (2).
Methodology: Different concentration of P. guajava L. Were in solution form then different Candida Albicans isolates were used to test the effectiveness of the extract on pathogen mentioned above. Different concentrations of p.guajava L. leaves powder were dissolved in different ethanol solution of 30% for maceration, were dissolved as follows 20g in 100ml of ethanol, 20g in 200ml in ethanol, 20g in 300ml of ethanol and 20g in 400ml of ethanol respectively to make the concentration of 0.2g/ml, 0.1g/ml, 0.07g/ml and 0.05g/ml after maceration the solution filtered and sterilized then were MIC against Candida albicans were tested.
Results: The best solvent extracts the highest level of tannin with ethanol by the value of tannin level 0.2g/ml. Different concentrations were used of ethanol 30% solvent to determine the effectiveness of tannin from p. guajava L. Leaves on pathogen Candida Albicans.
Conclusion: This study showed that ethanolic extract of psidium guajava 0.2/ml showed the Minimum Inhibitory Concentration against C.albicans infection.
| Item type | Current library | Collection | Status | Barcode | |
|---|---|---|---|---|---|
| UNDERGRADUATE DISSERTATIONS | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | NFIC | 1 | UD0432 |
Abstract:
Background: Guava leaves [psidium quajava Linn.] Myrtaceae. The plant is originated from Mexco spread throughout America. Europe, Africa and Asia. The tree of guava grows in the tropical and subtropical areas of the world in the different climatic conditions. Guava leaves are found in a small three which is 10m high with thin smooth patch, pealing bark. Leaves are opposite with short petiolate and has oval blade with prominent veins 5-15 cm long. (1) Guava leaf is reported that a green immature leaves contains sterols, tannins, proteins and aminoacids. However ever tannins investigated to have inhibitory activity in five different pathogens microbial like Escherichia Coli, Pseudomonas aurreginose, Staphylococcus aureas, Aspergillus niger and Candida albicans (2).
Methodology: Different concentration of P. guajava L. Were in solution form then different Candida Albicans isolates were used to test the effectiveness of the extract on pathogen mentioned above. Different concentrations of p.guajava L. leaves powder were dissolved in different ethanol solution of 30% for maceration, were dissolved as follows 20g in 100ml of ethanol, 20g in 200ml in ethanol, 20g in 300ml of ethanol and 20g in 400ml of ethanol respectively to make the concentration of 0.2g/ml, 0.1g/ml, 0.07g/ml and 0.05g/ml after maceration the solution filtered and sterilized then were MIC against Candida albicans were tested.
Results: The best solvent extracts the highest level of tannin with ethanol by the value of tannin level 0.2g/ml. Different concentrations were used of ethanol 30% solvent to determine the effectiveness of tannin from p. guajava L. Leaves on pathogen Candida Albicans.
Conclusion: This study showed that ethanolic extract of psidium guajava 0.2/ml showed the Minimum Inhibitory Concentration against C.albicans infection.
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