Adverse Drug Reactions Among AIDS Pregnant Women Receiving Anti-Retroviral Therapy at Prevention of Mother to Child Transmission Clinic at Bugando Medical Centre.
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Abstract:
Background: Mother to child transmission remains to be major source of new HIV infection worldwide. Safety data for anti-retroviral therapy during pregnancy were minimal especially at our setting, that’s why this study was conducted.
Methodology: Retrospective cross-sectional study was conducted from December 2017 to August 2018 at prevention of mother to child transmission clinic at Bugando medical centre. In which prevalence and management of reported ADRs was determined.
Results: Among 442 mothers examined only 60 mothers reported for ADRs. The most common ADR reported were rash due to Efavirenz 47 (78.3%) followed by GI upset due to Tenofovir 26 (43.3%). Others were Neutropenia nausea anaemia headache hang over and drowsiness.
Conclusion: This reassure that highly active ant-retroviral therapy has strong benefits for prevention of mother to child transmission as well as for maternal and infant’s morbidity and mortality reduction.
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