Heidi Fuller

Recovery of Motor Function Following Spinal Cord Injury - London: BoD – Books on Demand, c2016 - 330 pages

Restoration of motor function following spinal cord injury is a complex and challenging task. By reviewing emerging cellular, pharmacological, rehabilitative, as well as surgical approaches, this book seeks to highlight promising therapeutic strategies for the repair and regeneration of motor circuitry. The multidisciplinary nature of these approaches illustrates various routes to bridging the gap between the bench and the bedside and to identify the challenges that must be overcome in order to bring about a viable therapeutic strategy for spinal cord injury patients.

9789535124979 9535124978 = Common terms and phrases 5-HT2A receptors acid activation acute animals apoptosis assessment astrocytes autoimmune axon regeneration axonal growth axons bone marrow Brain Res cervical SCI chondroitinase ABC chronic clinical contusion cortical corticospinal cytokines differentiation dorsal horn effects evaluation Exp Neurol experimental expression following SCI functional recovery G-CSF glial scar growth factor hemisection human improved increased induced inflammatory inhibition inhibitory injection injured spinal cord injury model interneurons intrathecal JAK-STAT JAK-STAT pathway Journal lamina lesion levels locomotor macrophages mesenchymal stem cells mice microglia modulation motoneurons motor function motor recovery MSCs muscle myelin nerve grafts neural neurite neurological neurons neuroprotection Neurosci Neurotrauma neurotrophic factor oligodendrocyte organotypic orthoses paraplegic pathway peripheral nerve plasticity pluripotent potential promote protein PubMed PMID rat spinal cord role SCI patients sensory serotonin signalling slice cultures spinal cord injury sprouting STAT3 stimulation studies Tetraplegic therapeutic therapies thoracic tissue tracts transection trauma treatment vitro vivo walking

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