A pharmacology primer : techniques for more effective and strategic drug discovery /
Terry P. Kenakin.
- 4th ed.
- Amsterdam ; Boston : Academic Press, c2014.
- xix, 430 p. : ill. ; 29 cm.
Includes bibliographical references and index.
What is pharmacology? -- How different tissues process drug response -- Drug-receptor theory -- Pharmacological assay formats : binding -- Agonists : the measurement of affinity and efficacy in functional assays -- Orthosteric drug antagonism -- Allosteric modulation -- The optimal design of pharmacological experiments -- Pharmacokinetics -- Safety pharmacology -- The drug discovery process -- Statistics and experimental design -- Selected pharmacological methods -- Exercises in pharmacodynamics and pharmacokinetics.