TY - BOOK AU - Olivier C. Haas TI - Radiotherapy Treatment Planning: New System Approaches T2 - Advances in Industrial Control SN - 9781447108214 AV - RC271.R3H38 1998 U1 - 616.99'40642 21 PY - 2012/// CY - Control Theory and Applications Centre, Coventry University, Priory Street, Coventry CVl SFB, UK PB - Springer Science & Business Media KW - N2 - An in depth examination of many of the complex issues associated with planning and optimisation of intensity modulated radiotherapy treatment. It includes: a presentation of current practice, techniques and equipment used by medical physicists and others to deliver radiotherapy treatment; a systems modelling approach in the formulation of a beam model for optimisation, describing the effect of X-rays on human body tissues; a deterministic approach to the inverse problem in radiotherapy, based on weighted iterative least squares is modified to allow an adaptive scaling of the error to improve the performance of a general least squares algorithm; a guided random search methodology, based on genetic algorithms which is aimed at solving multi-objective optimisation problems is developed to optimise beam weight/wedge angle as well as coplanar beam orientation; the overall approach developed is demons trated practically using both traditional and modern measurement techniques ER -