TY - BOOK AU - Daniel M. Trifiletti AU - Samuel T. Chao AU - Arjun Sahgal AU - Jason P. Sheehan TI - Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy : A Comprehensive Guide SN - 9783030169237 PY - 2019/// CY - Mayo Clinic, Radiation Oncology Mayo Clinic School of Medicine Radiation Oncology Jacksonville, FL USA PB - Springer Nature Switzerland AG KW - Surgery N1 - Includes References and Index N2 - There are a large number of books on stereotactic radiotherapy. Some focus on specific techniques, and others on specific indications. Some books try to provide an overview of all available literature, often leaving the reader with many questions on how to do what in their specific situation for an individual patient. Well, this book is different! After the successful implementation of stereotactic techniques for intracranial lesions in the past century, stereotactic techniques have also become an important treatment option for extracranial tumors, and the role of stereotactic body radiotherapy (SBRT) for lung, liver, and spine lesions is now well established. Moreover, SBRT is being explored and advocated for tumors and functional indications at various other locations. In this book, the editors have done an excellent job in bringing together the information on all relevant topics in stereotactic radiosurgery (SRS) and SBRT. An impressive line-up of world-renowned experts provides an outstanding and comprehensive review of the biological aspects, radiation physics principles, clinical indications, and the available evidence. Instead of summing up all available literature, the chapters provide clearly written reviews with information which is scientific, but at the same time very practical and immediately applicable to daily clinic. In the chapters on biology, the rationale for SRS and SBRT and the mechanisms of action of the high-dose hypofractionated treatments are discussed. Latest insights on the interaction of radiotherapy with the immune systems are addressed as well. The chapters on SRS are partly technique-based, which enables the readers to have easy access to information on the techniques used at their centers. In a separate section, SRS is discussed in detail for the most frequent indications as well. For SBRT, the general physics aspects including immobilization and motion management are described in detail. A separate chapter focuses on the use SBRT using charged particles. Apart from the important mainstream indications such as lung and spine tumors, newer indications—such as SBRT for head and neck cancer, gastro-intestinal tumors, kidney tumors, and prostate cancer—are addressed in various chapters. The final chapters of this book provide an excellent overview of some general aspects, such as complication management and integration with other therapies, as well as of future directions of the rapidly emerging fields of SRS and SBRT. This book is written with the reader in mind who is looking for an up-to-date and state-ofthe-art overview of stereotactic radiotherapy for intra- and extracranial indications; Advancements in technology over the past several decades have created an atmosphere of multidisciplinary collaborative care that is very unlike medicine in the early twentieth century. Today, team-based approaches allow us to leverage techniques and modalities for the benefit of the patient. Radiosurgery is a perfect example of multidisciplinary collaboration and the benefit that specialization affords the patient, by blurring the lines between traditional medical specialities. Today, centers across the world have developed skills, techniques, and expertise in use of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) for treatment of many diseases. Perhaps stereotactic radiosurgery can be seen as a budding discipline of its own as it continues to gain distinction that differentiates it from the arenas of conventional surgery and radiation therapy. Unfortunately, the sharing of this practical knowledge has been limited to specialty-specific annual meetings, frequently with conflicting recommendations between medical disciplines. As a result, it is currently very difficult for a clinician (either in training or in practice) to gain experience and expertise in SRS and SBRT. Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy: A Comprehensive Guide was created for the purpose of centralizing the knowledge and experience of experts across a variety of disciplines. Our vision is that this book be used to serve as a basis for the current state of the art of SRS and SBRT. There is no doubt that advancements are made almost daily and refinements will be made as technology advances. However, for providers seeking to expand their knowledge and grow their radiosurgical skill set, this text will serve as a resource to allow for their development. We thank our gracious contributors for lending their expertise toward the further advancement of our field and toward the improved care of our patients. Their efforts to improve the care of patients cannot be overstated ER -