Background: The study of antibiotics use among adult inpatients enables to detect the inappropriate antibiotic use among adults admitted in the adult wards. Inappropriate antibiotic use has led to several health challenges such as (Antimicrobial resistance) AMR, increase of prolonged illness, longer hospital stays and the need for more expensive medicines. This study aimed to describe antimicrobial consumption in hospitals by Daily Defined Doses per hundred bed days (DDD/100BD) is used to standardize antimicrobial consumption data.
Methods: Retrospective cross-sectional hospital-bases study was conducted, by retrieving data from patient files who were admitted in the adult wards at Misungwi District Hospital starting from October 2019 to September 2020. Data was collected using convenience sampling and filled in the modified data collection tool then fed into Epicollect software and transformed to Microsoft excel for cleaning and transferred to Statistical Package for Social Sciences (SPSS) for analysis.
Results: A total of 545 admitted patient files were used for data collection. Out of 545 admitted patients, 399 (73.2%) patients were prescribed with antibiotics and 146 (26.8%) patients were not prescribes with antibiotics. Commonly prescribed antibiotics were ceftriaxone 172 (27.8%), metronidazole 149 (24.1%) and ampicillin/cloxacillin 108 (17.5%), Overall DDD/100BD was 74.8. Out of 399 patients prescribed with antibiotics, 252 (63.2%) had prescription on common diseases. Prescriptions that completely adhered to national STG were 100 (40%), those that partially adhered 66 (26%) and non-adherence was 86 (34%).
Conclusion: An effort must be made to improve appropriate use of antibiotics by rising awareness among prescribers and enforcing implementation and use of STG. This will help to increase total adherence and reduce partial and non-adherence.