Preparative Chromatography Of Fine Chemicals and Pharmaceutical Agents. - London | WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim | 2005. - 487 Pages

This interdisciplinary approach combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. The book covers recent developments in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants.

Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on solid materials and packed columns process concepts. Final chapters on modeling and determination of model parameters, the design and optimization of preparative chromatographic processes and chromatographic reactors allow for the optimum selection of chromatographic systems.

Essential for chemists and engineers working in the chemicals and pharmaceutical industries as well as for food technologies, due to the interdisciplinary nature of these processes.

ISBN: 978-3-527-30643-5 3-527-30643-9 = Preparative Chromatography Of Fine Chemicals and Pharmaceutical Agents acetonitrile adsorbent adsorption analytical applied axial dispersion batch calculated Chapter chemical chiral chro chromatographic processes chromatographic reactors chromatographic separation chromatographic system coefficient concentration profile cp,i desorbent detector determined diffusion dimensionless eluent consumption elution enantiomer Eq equilibrium experimental feed concentration Fig Figure flow rate fluid fraction fructose function glucose gradient groups Guiochon HETP HPLC hydrophobic increase injection inlet isocratic Langmuir linear liquid mass balance mass transfer methanol method mIII mixture mobile phase mobile phase composition model parameters molecules multi-component nonlinear number of columns number of stages operating parameters optimization outlet packed bed packing peak plant plate number polar polymers pore porosity preparative chromatography pressure drop pump purity R-enantiomer racemic raffinate reactant reaction recycling retention retention factor reversed phase RP sample selectivity silanol silica simulation SMB processes SMBR solubility solute solvent solvent strength stationary phase surface switching tion TMB uint velocity volume ε

Subjects--Personal Names: --Science / Chemistry / General, Technology & Engineering / Chemical & Biochemical, Chromatographic analysis, Drugs -- Analysis.