Nasopharyngeal Cancer Multidisciplinary Management.
- London | Springer-Verlag Berlin Heidelberg | 2010.
- 336 Pages
- Diagnostic Imaging and Radiation Oncology. .
The past decade has witnessed significant progress in the diagnosis and treatment of nasopharyngeal cancer. Radiation therapy, used with curative intent, has undergone important technological advances, and combined chemotherapy and radiation has also become an established option. As a result, outcomes among patients with localized disease have improved markedly, with higher overall survival, better locoregional disease control, less treatment-induced toxicity, and better quality of life. However, most of the developments that have taken place are complex, and often not fully understood by physicians in general oncology practice without specialization in the treatment of head and neck cancer.
Against this background, Nasopharyngeal Cancer - Multidisciplinary Management aims to provide a comprehensive account of the current state of knowledge of nasopharyngeal cancer and its multidisciplinary management. The first ten chapters contain essential information on subjects such as epidemiology, pathogenesis, molecular biology, pathology, and the use of imaging in diagnosis and staging. Subsequent chapters examine in depth the various treatment options and explain combinations in a range of settings. Detailed attention is given to the roles of concurrent, adjuvant, and neoadjuvant chemotherapy and advanced radiotherapy techniques. Further chapters then explore surgical options, follow-up, treatment of metastatic disease, treatment-related and complications and nasopharyngeal cancer in children. This is an important book that meets an urgent need and will prove essential reading for the oncology community worldwide.
978-3-540-92810-2 978-3-540-92809-6
0942-5373
= Nasopharyngeal Cancer Multidisciplinary Management adjuvant chemotherapy advanced nasopharyngeal carcinoma AJCC angiogenesis anti-EBV antibody brachytherapy Cancer Res carboplatin cetuximab Chan chemoradiation chemoradiotherapy Chen cisplatin Clin Oncol clinical concurrent cranial nerve CT detection diagnosis disease DNA dose EBV EBV DNA EGFR Epstein-Barr virus familial NPC Fig follow-up fossa fractionation geal gemcitabine genes growth factor Gy head and neck Head Neck Hong Kong imaging IMRT Int J Radiat intensity-modulated irradiation Kwong Lee AW Leung SF Lin LMP1 locally advanced locoregionally advanced lymph nodes malignancies median metastasis metastatic MRI nasopha nasopharyngeal cancer nasopharyngeal carci nasopharyngeal carcinoma neck cancer nodal noma NPC patients Oncol Biol Phys Oncology outcome overall survival paclitaxel parapharyngeal patients treated patients with nasopharyngeal pediatric primary tumor prognostic factor protein Radiat Oncol Biol radiation therapy Radiother radiotherapy recurrent regimen regions reported retropharyngeal risk RT ryngeal carcinoma Sham significant Singapore squamous cell carcinoma Teo tion tissue TNM toxicity tumor volume VEGF Wang xerostomia
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