Nano Drug Delivery for Cancer Therapy Principles and Practices - Stem Cell Research Imam Abdulrahman Bin Faisal University Dammam, Saudi Arabia | Springer Nature Singapore Pte Ltd | 2023. - 259 Pages Includes References

This book discusses the various modes and methods of nano-based drug delivery in different types of cancers such as colon, breast, cervical, ovarian, and lung cancer. It reviews the significance of nano drug delivery in cancer therapy, the application of nanoparticles in overcoming drug resistance, targeted therapy, and immunotherapy. The book also covers topics related to the synthesis of different types, shapes, and sizes of nanocarriers using synthetic and biological approaches. Further, a chapter explores the synthesis of nanocarriers loaded with anti-cancer drugs by using functionalization or conjugations and encapsulation methods. The book also examines the nanocarriers as delivery vehicles for chemotherapeutic agents against cancers using in vitro and animal models of cancers, preclinical trials for efficacy, and safety profiling of nanocarriers. Finally, future trends and innovation in nano drug delivery for cancer therapy, application of siRNA (nanoparticle-based RNA) therapy, ultrasound-linked nano-cancer therapeutics, and application of exosome-based cancer therapy topics are discussed. Towards the end, the book examines the limitations of nanocarriers, including the cell and tissue toxicity, genotoxicity, and scale-up of nanomaterials, health and environmental hazards associated with nanoformulation synthesis, respiratory diseases, government regulations, and ethical issues.

ISBN: 978-981-99-6939-5 978-981-99-6940-1 (eBook) = acid agents anticancer drugs antigen apoptosis biocompatibility biodegradable biological biomedical applications breast cancer cancer therapy cancer treatment carbon nanotubes carriers cellular Chem chemical chemotherapeutic chemotherapy Chen clinical trials conjugated curcumin cytotoxicity dendrimers diseases DNA docetaxel DOX doxorubicin drug delivery drug delivery systems drug loading drug release drug resistance effects efficacy encapsulated enhanced Epub exosomes Fig functionalized gene genotoxicity gold nanoparticles graphene graphene oxide Green synthesis H human hydrophobic immune system immunotherapy improve increase inorganic interaction Khan lipid liposomes Liu lung cancer magnetic materials membrane mesoporous silica metal method micelles models molecules nano-based nanocarriers nanomaterials nanomedicine nanomedicine products nanoparticle-based nanoparticles nanoplatforms nanoscale nanosystems nanotechnology nm NPs oxide nanoparticles paclitaxel particles PEGylated peptide pH phase PLGA PMCID PMID polymer polymeric potential properties protein receptors Sci siRNA Spherical stability Status Study results structure surface temperature theranostics therapeutic tissues toxicity tumor tumor cells types ultrasound uptake various vitro vivo Wang zebrafish Zhang ZnO.

Subjects--Personal Names: --Cancer, Medical / Oncology / General, Nanobiotechnology, Nanomedicine, Science / Biotechnology, Science / Life Sciences / Genetics & Genomics, Technology & Engineering / Materials Science / General, Cancer -- Chemotherapy -- Technological innovations, Drug delivery systems.