Liver Fluke, Opisthorchis viverrini Related Cholangiocarcinoma Liver Fluke Related Cholangiocarcinoma - Department of Surgery Khon Kaen University Khon Kaen, Thailand | Springer Nature Switzerland AG | 2023 - Recent Results in Cancer Research .

This volume discusses new developments in the etiology, diagnosis, and treatment of cholangiocarcinoma induced by the liver fluke Opisthorchis viverrini. Although cholangiocarcinoma is rare in the Western world, it has a very high incidence in continental Southeast Asian countries, where it is linked to infection with O. viverrini. In Southeast Asia this cancer causes thousands of deaths every year and places a severe socioeconomic burden on the affected families. Diagnosis is usually at a late disease stage, and in the past palliative surgery and care have been the major therapeutic options. Recently, however, techniques have become available for early-stage diagnosis that offer the possibility of curative surgery, and novel chemotherapeutic options are also under development. In Thailand alone, more than 2 million individuals have now been registered for screening for this cancer. The aim of this book is to highlight the latest research in the field and to explain how the newly available techniques can be applied to reduce the risk of developing cholangiocarcinoma and increase the likelihood of survival.

978-3-031-35165-5 978-3-031-35166-2 (eBook)

0080-0015 2197-6767 (electronic) = Andrews RH bile duct biliary drainage biliary tract cancer Bithynia Cambodia CASCAP catheter CCA cell CCA patients Chamadol chemotherapy cholangiocarcinoma cholangitis clinical Cohort cyprinid diagnosis dilatation disease dissection distal DNA extrahepatic Fig gemcitabine genetic hepatectomy hepatic artery hepatic duct hepatic vein hepatobiliary hilar iCCA imaging intraductal intrahepatic CCA intrahepatic cholangiocarcinoma invasion Isan Khon Kaen University Khuntikeo Lao PDR left hepatic liver fluke Loilome lymph node mass-forming Mekong metacercariae metastasis molecular mutations Namwat neoadjuvant northeast Thailand Oncol opisthorchiasis Opisthorchis viverrini OV palliative palliative care pancreatic parasite Parasitol perihilar CCA perihilar cholangiocarcinoma Petney TN population portal vein pre-operative prevalence prognosis protein Province PTBD public health Pubmed Central Pubmed Central PMCID PubMed PMID raw fish region related CCA resection right hepatic risk factors screening segment siamensis Sithithaworn snails species stent Surg surgery surgical survival targeted therapy Thinkhamrop tissue transection treatment trematode tumor ultrasound vascular versus Yongvanit

--Bile ducts -- Cancer, Gastroenterology, Liver flukes, Oncology, Opisthorchis viverrini, Parasitology.