TY - BOOK AU - TI - Tumors of the Central Nervous System: Gliomas T2 - Tumors of the Central Nervous System SN - 978-94-007-0343-8 U1 - 616.994 HAY PY - 2011/// CY - London | PB - Springer Science+Business Media B.V | KW - N2 - The most recent developments in diagnostic and therapeutic aspects of Gliomas (Glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers is included. The identification and validation of brain cancer (glioblastoma) genes are discussed. Role of cancer stem cells in the initiation, progression, and persistence of malignant gliomas is explained. The use of surgical resection, chemotherapy (e.g., temozolomide), immunotherapy, and radiotherapy for malignant glioblastoma are pointed out. Standard (established) as well as newer imaging modalities (proton magnetic resonance spectroscopy) are discussed UR - DOI 10.1007/978-94-007-0344-5 ER -