Prevalence and factors associated with true resistant hypertension among patients with apparent resistant hypertension at Bugando medical centre and Sekou-toure regional referral hospital in Mwanza, Tanzania.
- Mwanza, Tanzania | Catholic University of Health and Allied Sciences [CUHAS-Bugando] | 2023.
- Pages xii-82 Includes References
Abstract:
Introduction: Resistant hypertension is associated with increased cardiovascular events (coronary heart disease, heart failure and myocardial infarction), end stage renal disease, stroke and death globally. There is no data on resistant hypertension prevalence and its associated factors in Tanzania. We aimed to investigate the prevalence and factors associated with true resistant hypertension at Bugando Medical Centre and Sekou-Toure Regional Referral hospital in Mwanza, Tanzania.
Methodology: We conducted a cross-sectional study in outpatient clinics at Bugando Medical Centre (BMC) and Sekou-Toure Regional Referral Hospital. Hypertensive patients were consecutively screened to determine patients with apparent resistant hypertension using office blood pressure measurement. Ambulatory blood pressure monitoring was further done to determine patients with true resistant hypertension. Associated factors were analyzed using logistic regression model.
Results: Of 4,241 hypertension patients, 18% (788) had apparent resistant hypertension. Among 329 uncontrolled apparent resistant hypertension patients, 30% (100) had true resistant hypertension. A total of 329 participants were included in the final analysis. Among the participants, 55% (180) were males and the median age was 68 [59-76] years. Only 45% (147) of participants had good medication adherence. Longer duration of hypertension (AOR 1.13; 95% CI 1.37 -4.11; p-value = 0.002) were found to be significantly associated with true resistant hypertension.
Conclusion: Prevalence of apparent resistant hypertension is high among Tanzanians in Mwanza. True resistant hypertension constitutes about a third of the uncontrolled apparent resistant hypertensive patients in the region. Concerted efforts are required in the management of resistant hypertension to mitigate poor cardiovascular outcomes, and special efforts should be undertaken to reduce nonadherence to anti-hypertensive medication.
Wurzburg Road 35, Premises, Post Code: 33102 | P. O. Box 1464 Mwanza, Tanzania | Phone: (255) 28-298-3384 | Fax: (255) 28-298-3386 | Email: vc@bugando.ac.tz | Website: www.bugando.ac.tz