TY  - BOOK
AU  -  Eligi, Karoli. Kimosso
AU  - Mirambo, Mariam
AU  - Mshana, Stephen. E
TI  -  Prevalence and Associated Factors of Hepatitis B Surface Antigen Among Pregnant Women Attending Antenatal Clinic at Makole Health Centre in Dodoma, Tanzania
PY  - 2019///
CY  - Mwanza, Tanzania:  
PB  - Catholic University of Health and Allied Sciences [CUHAS – Bugando],   Phone: +255 28 298 3384,   Fax: +255 28 298 3386,     Email: vc@bugando.ac.tz,   Website: www.bugando.ac.tz
KW  -  
N2  - Abstract:

Background and Objectives: HBV infection during pregnancy can result into adverse pregnancy outcomes. In Tanzania, HBV vaccination is not offered among reproductive aged women which put them at high risk of transmitting the infection during pregnancy. Despite being common in Tanzania, there is scarcity of information on HBV among pregnant in Dodoma. This study aim at determining prevalence of HBsAg and associated factors among pregnant women at Makole Health centre in Dodoma.

Methodology: Analytical cross sectional hospital based study involving 300 pregnant women was carried out from May to June 2019 at Makole health centre in Dodoma. Socio demographic, obstetrics and other relevant information collected by using structured data collection tool. About 5ml of blood collected aseptically and plasma was used for detection of hepatitis B surface antigen by using immunochromatographic test. Data was analyzed by STATA version 13 as per study objectives.

Results: The mean age of enrolled women was 26.27 ± 6.03 years and mean gestation age was 22.05 ± 8.33 weeks. Prevalence of HBsAg was found to be 10(3.33%, 95% CI: 2.797-3.863). Low education level (OR5.1683, 95% CI: 1.3019-28.9506, p=0.022) were found to independently predict HBsAg positivity on multivariate logistic regression analysis.

Conclusion: The study has found intermediate prevalence of HBV infection among pregnant women attending antenatal clinic at Makole health centre which was predicted by history of a baby with low birth weight and low education level. Emphasis on control measures including vaccinating reproductive aged women are recommended in Tanzania and other developing countries where HBV is endemic.

ER  -