Association of Schistosome Infection with Adiposity in Tanzania
- Mwanza, Tanzania: Frontiers Catholic University of Health and Allied Sciences [CUHAS – Bugando] 12 December 2022
- Pages 5027
- [CITATION] Association of Schistosome Infection with Adiposity in Tanzania K Pham, G PrayGod, D Faurholt-Jepsen, MF Olsen… - Frontiers in Public … - Frontiers Frontiers in Public Health Volume 10 .
Background: Observational studies in humans have reported a link between schistosome infection and lower adiposity, but this may be explained by socioeconomic and demographic factors, intensity of infection, or common co-infections such as HIV.
Methods:This was a cross-sectional study that investigated the relationship between schistosome infection and adiposity in a large, well-described cohort of Tanzanian adults living with and without HIV. Cross-sectional data were collected among adults living in Mwanza, Tanzania who were enrolled in the Chronic Infections, Co-morbidities and Diabetes in Africa (CICADA) cohort study. Schistosome circulating anodic antigen, secreted by both Schistosoma mansoni and haematobium which are endemic to Tanzania, was quantified from stored samples. Schistosome infection diagnosed by serum circulating anodic antigen levels. The primary outcome was fat mass …