TY - BOOK AU - Christine Joyce AU - Adolphine Hokororo AU - Joy Howell AU - Paul Christos AU - Robert Peck TI - 455: Resistance Patterns and Clinical Predictors of Pediatric Bacteremia at a Tanzanian Hospital PY - 2015////12/1 CY - Mwanza, Tanzania: PB - LWW &, Catholic University of Health and Allied Sciences [CUHAS – Bugando] N2 - Methods: This retrospective chart review evaluated all blood cultures performed in pediatric inpatients aged 0–12 over 1 year at a Tanzanian hospital. Positive cultures and resistance patterns were recorded. Charts were reviewed and compared on a cohort of positives and negatives using chi-square and Fisher’s exact tests. Given the study’s exploratory nature and small sample size, all p-values< 0.25 were reported for hypothesis-generating purposes. Results: A total of 585 blood cultures were reviewed from 523 patients; 51 cultures were positive (20 gram positive, 31 gram negative), indicating a bacteremia prevalence of 8.7%. Of those tested against the first line regimen of ampicillin and gentamicin, 60%(14/23) were resistant. Of those tested against the second line regimen of Ceftriaxone, 75%(3/4) were resistant. Of the gram-positives, 75%(15/20) were Staph Aureus. Of these, 33%(5/15) were Methicillin ER -