TY - BOOK AU - A Vera AU - D Abramovitz AU - H Staines AU - G Rangel AU - G Martinez AU - R Lozada AU - S Strathdee AU - T Visser AU - J Kachuchuru AU - C Chenha AU - DJ Matungwa AU - M Cobbler AU - RM Ochieng AU - C Magis‐rodriguez AU - T Bondar AU - O Balakireva AU - O Sakovych AU - S Brady AU - J Bacic AU - C Mainville AU - J Wolfe AU - K Reid AU - M Richardson AU - J Berger‐greenstein AU - J Bendezu AU - M Schuster AU - M Wachman AU - D Klein AU - T Patterson AU - Y Toefy AU - I Thurston AU - D Skinner AU - L Bogart AU - C Halpern AU - T Bärnighausen AU - H Thirumurthy AU - A Pettifor AU - S Handa AU - M Godwaldt AU - S Eggermont AU - MA Bekalu AU - N Ncitakalo AU - N Wabiri AU - L Simbayi AU - G Matseke AU - S Olango AU - V Kutai AU - S Wangila AU - J Nyagero AU - D Ilic AU - D Nordlund AU - B Adjei AU - C West AU - C Jones AU - C Irizarry AU - SM Mukhopadhyay AU - I Hansen AU - M Lichtenberg AU - S Humair AU - D Bloom AU - C Jiraphongsa AU - W Chaitha AU - J Simoni AU - M van Reeuwijk AU - S Cohn AU - N Lambert AU - T Rasberry AU - M Andrasik AU - M Desmond AU - D Rao AU - K Shannon AU - J Chettiar AU - J Montaner AU - O Amram AU - C Feng AU - K Deering AU - M Suba AU - D Brewster‐lee AU - A Mbi AU - A Tchouamo AU - B Bagfegue Ekani AU - AE Njom Nlend AU - G Rebchook AU - J Sevelius AU - L Gutierrez‐mock AU - J Keatley AU - D Castro AU - A Babu Ndyabahika AU - C Kiiza AU - S Gregson AU - L Sherr AU - M Skovdal AU - K Scott AU - C Madanhire AU - C Nyamukapa AU - M Nhamo AU - C Campbell AU - M Makokha AU - A Itaka AU - G Mshana AU - J Changalucha AU - J Francis AU - I Kalongola AU - A Massawe AU - G Maro AU - T Lim AU - L Langhaug AU - P Amman AU - K Wespi AU - A Gschwend AU - J Brion AU - P Reid AU - P Chaiphibalsarisdi AU - D Wantland AU - M Rivero‐mendez AU - J Kemppainen AU - K Nokes AU - S Iipinge AU - PK Nicholas AU - KM Sullivan AU - L Tyer‐viola AU - C Portillo AU - IB Corless AU - LS Eller AU - E Sefcik AU - J Voss AU - K Kirksey AU - MO Johnson AU - W Chen AU - WL Holzemer AU - C Dawson Rose AU - A Webel AU - JC Phillips AU - L Brody AU - M Cohen AU - K Weber AU - S Dale AU - R Cruise AU - G Kelso AU - S Legrand AU - E Wilson AU - K Whetten AU - S Reif AU - I Chaitha AU - R Pibulniyom AU - S Kaeworasan AU - W Isaranun AU - L Sung‐jae AU - L Lili AU - S Khumthong TI - Track D Social Science, Human Rights and Political Science PY - 2012/// CY - Mwanza, Tanzania: PB - Wiley Periodicals, Inc. &, Catholic University of Health and Allied Sciences [CUHAS – Bugando] N2 - Abstract: Background: We evaluated brief combination interventions to simultaneously reduce sexual and injection risks among female sex workers who inject drugs (FSW-IDUs) in Tijuana (TJ) and Ciudad Juarez (CJ) Mexico during 2008-2010, when harm reduction was expanding in TJ, but not CJ. Methods: FSW-IDUs≥18 years reporting recently sharing injection equipment and unprotected sex with clients participated in a randomized factorial trial comparing four brief, single-session combinations of active motivational-interviewing and didactic interventions focused on negotiating safer-sex in the context of drug use and safer-injection skills. The injection intervention included a video made by FSW-IDUs. Women underwent quarterly interviews and testing for HIV, syphilis, gonorrhea, Chlamydia and Trichomonas. Poisson regression with robust variance estimation and repeated measures ordinal logistic regression via GEE examined effects on HIV/STI incidence and receptive needle sharing frequency, respectively. Results: Of 599 initially HIV-negative FSW-IDUs (TJ: N=296; CJ: N=303), quarterly retention was≥90%. After 12 months, HIV/STI incidence decreased >50% in the active vs. didactic sex intervention (TJ: AdjRR:0.41, 95%CI: 0.18–0.91, p=0.03; CJ: AdjRR: 0.44, 95%CI: 0.19–0.99, p=0.05)-see tables. In CJ, women receiving active vs. didactic injection risk interventions decreased receptive needle-sharing by 84% vs. 71%, respectively (p=0.05); in TJ, receptive needle-sharing declined by 95%, but was similar in active vs. didactic groups (p=0.54). TJ women reported significant increases in access to syringes and condoms, but CJ women did not-see figure. Conclusion: In both cities, a 30-minute intervention promoting safer-sex in the context of drug use significantly reduced HIV/STI incidence with sustained effects at 12 months. Expanding free access to sterile syringes coupled with brief, didactic education on safer injectionwas both necessary and sufficient in achieving dramatic, sustained injection risk reductions in TJ. In the absence of expanding syringe access in CJ, the injection risk intervention still achieved significant, albeit more modest reductions, suggesting that community-level interventions incorporating harm reduction are more powerful than individual-level interventions for reducing injection risks. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499903/ ER -