Prevalence and factors associated with Mycobacteremia and mortality among febrile HIV infected patients in Mwanza, Tanzania
- Mwanza, Tanzania: Elsevier & Catholic University of Health and Allied Sciences [CUHAS – Bugando] 2018/5/1
- Pages 69-71
- International Journal of Infectious Diseases Volume 70 .
Abstract:
Objectives: This study investigated the prevalence and factors associated with mycobacteremia and mortality among febrile HIV infected patients in developing countries.
Methods: A hospital based cross-sectional study was conducted among febrile HIV patients admitted at Bugando Medical centre and Sekou Toure hospital between November 2016 and March 2017. Blood culture was done on BACTEC Myco/F Lytic bottles. Clinical and demographic data were collected using a pre-tested data collection tool.
Results: A total of 154 patients with the mean age of 41.5 ± 12.2 were enrolled. Females formed the majority, 93 (60%) of the study participants. The prevalence of Mycobacteremia was 3.3% while that of other bacteria was 8.4%. Age (p = 0.03), recent HIV diagnosis (p = 0.005), not taking HAART (p = 0.031) and low CD4+ count (p = 0.002) were significantly associated with Mycobacteremia. Factors significantly associated with 14-day in-hospital mortality were advanced HIV infection (p < 0.001), poor ART adherence (p < 0.001), low CD4+ (p = 0.0002) and Mycobacteremia (p = 0.007).
Conclusion: The prevalence of Mycobacteremia was low; however, it was significantly associated with mortality. Mycobacteremia should be suspected in high risk febrile HIV infected individuals followed by early appropriate treatment in order to reduce associated morbidity and mortality.