TY - BOOK AU - Pius G Horumpende AU - Sophia H Said AU - Jaffu O Chilongola AU - Debora C Kajeguka AU - Blandina T Mmbaga AU - Stephen E Mshana AU - Festo S Mazuguni AU - Charles E Mwanziva AU - Tolbert B Sonda AU - Magreth L Antony AU - Happiness H Kumburu TI - Prevalence, determinants and knowledge of antibacterial self-medication: A cross sectional study in North-eastern Tanzania PY - 0000/// October 312018/// CY - Mwanza, Tanzania: PB - Public Library of Science &, Catholic University of Health and Allied Sciences [CUHAS – Bugando] N2 - Abstract Self-medication is very common especially in developing countries and is documented to be associated with many health risks including antibiotic resistance. This study investigated the prevalence, determinants and knowledge of self-medication among residents of Siha District in Tanzania. A cross-sectional study was conducted among 300 residents in a rural District of Kilimanjaro region, North-eastern Tanzania from 1st to 28th April 2017. A semi-structured questionnaire was used to collect information regarding drugs used, knowledge, history and reasons for antibiotic self-medication. Log—binomial regression analysis was done using STATA 13 to examine factors associated with self-medication. A slightly majority of the respondents (58%) admitted to self-medication. Antibiotics most commonly utilized were amoxycillin (43%) and an antiprotozoal drug metronidazole (10%). The most common symptoms that led to self-medication were cough (51.17%), headache/ fever/ malaria (25.57%) and diarrhoea (21.59%). The most common reasons for self-medication were emergency illness (24.00%), health facility charges (20.33%), proximity of pharmacy to home (17.00%) and no reason (16.66%). Almost all reported that self-medication is not better than seeking medical consultation, 98% can result into harmful effects and 96% can result to drug resistance. The level of self-medication in this study is comparable with findings from other studies in developing countries. Pharmacies were commonly used as the first point of medical care. There is therefore a need for educative antibiotic legislative intervention to mitigate the adverse effects of antibiotic self-medication in Siha district in Tanzania UR - https://doi.org/10.1371/journal.pone.0206623 ER -