TY - BOOK AU - Pierre,Valérie C. AU - Allen,Matthew John ED - Royal Society of Chemistry (Great Britain), TI - Contrast agents for MRI: experimental methods T2 - New developments in NMR, SN - 9781782624479 (hbk.) AV - RC78.7.C65 C654 2018 U1 - 616.07/575 23 PY - 2018///] CY - Cambridge PB - Royal Society of Chemistry KW - Contrast-enhanced magnetic resonance imaging KW - Experiments KW - Contrast media (Diagnostic imaging) KW - Magnetic resonance imaging KW - Contrast Media KW - Magnetic Resonance Imaging KW - methods N1 - Includes bibliographical references and index N2 - "As a practical reference guide for designing and performing experiments, this book focuses on the five most common classes of contrast agents for MRI namely gadolinium complexes, chemical exchange saturation transfer agents, iron oxide nanoparticles, manganese complexes and fluorine contrast agents. It describes how to characterize and evaluate them and for each class, a description of the theory behind their mechanisms is discussed briefly to orient the new reader. Detailed subchapters discuss the different physical chemistry methods used to characterize them in terms of their efficacy, safety and in vivo behavior. Important consideration is also given to the different physical properties that affect the performance of the contrast agents. The editors and contributors are at the forefront of research in the field of MRI contrast agents and this unique, cutting edge book is a timely addition to the literature in this area."-- ER -