TY  - BOOK
AU  - Zhou,Honghui
AU  - Mould,Diane R.
TI  - Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases
SN  - 9781119289210
AV  - RC600 
U1  - 616.97/806 23
PY  - 2019///
CY  - Hoboken, NJ
PB  - Wiley
KW  - Autoimmune Diseases
KW  - drug therapy
KW  - Proteins
KW  - therapeutic use
KW  - pharmacokinetics
KW  - Protein Engineering
KW  - methods
KW  - Models, Theoretical
N1  - "John Wiley & Sons Inc."--tp verso; Includes bibliographical references and index
N2  - "Focused on quantitative pharmacology and individualized therapy for developing biotherapeutics in immune-mediated inflammatory diseases, this book discusses both theoretical and practical aspects and includes case studies illustrating applications in drug development. Provides frontline knowledge of using PK/PD modeling tools to address a variety of problems in development of therapeutic proteins. Reviews and discusses biomarkers, systems pharmacology, PBPK modeling, and target-mediated modeling, as translational tools. Helps readers understand disease progression and identify of mechanisms-based biomarkers with clinical relevance"--Provided by publisher
ER  -