Contents:

Impact of Microbes on the Intestinal Development of the Preterm Infant


Microbiome Allergic Diseases of Childhood


Pathogenesis Immunity and the Role of MicrobiomeProbiotics in Enteric Virus Infections in Humans and Animal Models


Enteric Bacterial Regulation of the WntβCatenin Signaling


Mechanisms Underlying the Beneficial Role of Probiotics in Diarrheal Diseases HostMicrobe Interactions


The Influence of Microbiota on Gastrointestinal Motility


Altered Microbiota and Their Metabolism in Host Metabolic Diseases


The Influence of the Microbiota on the Etiology of Colorectal Cancer


Oral Microbiome Potential Link to Systemic Diseases and Oral Cancer


Candida albicans Commensalism and Human Diseases


Fecal Microbiota Transplants Current Knowledge and Future Directions


Statistical Models and Analysis of Microbiome Data from Mice and Humans


Index

Only recently have we begun to appreciate the role of microbiome in health and disease. Environmental factors and change of life style including diet significantly shape human microbiome that in turn appears to modify gut barrier function affecting nutrient & electrolyte absorption and inflammation. Approaches that can reverse the gut dysbiosis represent as reasonable and novel strategies for restoring the balance between host and microbes.

In the book, we offer summary and discussion on the advances in understanding of pathophysiological mechanisms of microbial host interactions in human diseases. We will not only discuss intestinal bacterial community, but also viruses, fungi and oral microbiome. Microbiome studies will facilitate diagnosis, functional studies, drug development and personalized medicine. Thus, this book will further highlight the microbiome in the context of health and disease, focusing on mechanistic concepts that underlie the complex relationships between host and microbes.