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Basis and Treatment of Cardiac Arrhythmias

By: Contributor(s): Material type: TextTextSeries: ; Volume 171 of Handbook of Experimental Pharmacology Publication details: Department of Pharmacology 630 W. 168 St. New York, NY 10032; Springer Science & Business Media c2006Edition: illustratedDescription: 361 pages ISBN:
  • 3540297154
  • 9783540297154
Subject(s): DDC classification:
  • 616.1/28 KAS
Contents:
Contents: HistoryofArrhythmias Mechanisms of Arrhythmias Conclusions Proarrhythmia Cardiac Na+ Channels as Therapeutic Targets Structural Determinants of Potassium Channel Blockade A Role for CalciumCalmodulinDependent Protein Kinase II AKAPsasAntiarrhythmicTargets? βBlockersasAntiarrhythmicAgents MutationSpecific Pharmacology of the Long QT Syndrome TherapyfortheBrugadaSyndrome Molecular Basis of Isolated Cardiac Conduction Disease hERG Trafficking and Pharmacological Rescue
Summary: This book incorporates the most up-to date information related to mechanisms and treatment of cardiac arrhythmia. Many of the topics discussed in this text reflect very recently undertaken research directions including genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These new approaches and implementations of anti-arrhythmic therapy derive from many decades of research as outlined in the first chapter by distinguished Professors Michael Rosen (Columbia University) and Michiel Janse (University of Amsterdam). The text covers changes in approaches to therapy over time, arrhythmias in multiple cardiac regions and over many scales, from gene to protein to cell to tissue to organ.
Item type: E-BOOKS
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Holdings
Item type Current library Collection Call number Status Barcode
E-BOOKS MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO NFIC 616.1/28 KAS (Browse shelf(Opens below)) -1 EBS12569
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Contents:

HistoryofArrhythmias

Mechanisms of Arrhythmias

Conclusions

Proarrhythmia

Cardiac Na+ Channels as Therapeutic Targets

Structural Determinants of Potassium Channel Blockade

A Role for CalciumCalmodulinDependent Protein Kinase II

AKAPsasAntiarrhythmicTargets?

βBlockersasAntiarrhythmicAgents

MutationSpecific Pharmacology of the Long QT Syndrome

TherapyfortheBrugadaSyndrome

Molecular Basis of Isolated Cardiac Conduction Disease

hERG Trafficking and Pharmacological Rescue

This book incorporates the most up-to date information related to mechanisms and treatment of cardiac arrhythmia. Many of the topics discussed in this text reflect very recently undertaken research directions including genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These new approaches and implementations of anti-arrhythmic therapy derive from many decades of research as outlined in the first chapter by distinguished Professors Michael Rosen (Columbia University) and Michiel Janse (University of Amsterdam). The text covers changes in approaches to therapy over time, arrhythmias in multiple cardiac regions and over many scales, from gene to protein to cell to tissue to organ.

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