Biopsy Diagnosis of Peripheral Neuropathy

By:

Juan M Bilbao

Contributor(s):

Robert E Schmidt

Material type: Text

TextPublication details: Sunnybrook and St Michael’s Hospitals University of Toronto Toronto , ON Canada Springer 2014 Edition: 2nd Edition, illustrated, revisedDescription: 486 pagesISBN:

3319073117
9783319073118

Subject(s):

Contents:

Contents Peripheral Neuropathy and the Role of Nerve Biopsy Normal Anatomy of the Peripheral Sural Nerve Quantitative Techniques The Axon Normal Structure and Pathological Alterations Schwann Cells and Myelin in the Peripheral Nervous System The Peripheral Nerve Vasculature Examination of the Peripheral Nerve Biopsy Clinical Aspects of Peripheral Neuropathy Leprous Neuropathy Vasculitic Neuropathy Dysproteinemic Neuropathies Amyloid Neuropathy Neuropathy Associated with Neoplasia Neuropathy Associated with Endocrine and Metabolic Disease Toxic Neuropathies Genetically Determined Neuropathies The Inflammatory Demyelinating Neuropathies Idiopathic Inflammatory Neuropathies Infectious Diseases Causing Neuropathy Storage Diseases Unclassified Neuropathies and Mimics

Summary: Peripheral nerve analysis is a challenging task for pathologists, given the advent of new diagnoses and techniques of analysis and the impact of molecular genetics. This book presents a simple, logical method for constructing a differential diagnosis based on pathology and clinical presentation. It also provides advice on the selection of ancillary molecular, immunohistochemical and genetic techniques to establish a definitive diagnosis. Clear, authoritative guidance is offered on diagnosis of the full range of neuropathies with the aid of a wealth of high-quality color photomicrographs and electron micrographs. The pathologist will benefit greatly from the identification of a variety of artifacts and normal structures occasionally encountered in nerve biopsies that need to be distinguished from specific pathologic alterations. This user-friendly, practical text will be an invaluable aid in achieving the most specific diagnosis possible.

Item type: E-BOOKS

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Item type	Current library	Collection	Status	Barcode
E-BOOKS	MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO	NFIC	-1	EBS10865

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Contents

Peripheral Neuropathy and the Role of Nerve Biopsy

Normal Anatomy of the Peripheral Sural Nerve

Quantitative Techniques

The Axon Normal Structure and Pathological Alterations

Schwann Cells and Myelin in the Peripheral Nervous System

The Peripheral Nerve Vasculature

Examination of the Peripheral Nerve Biopsy

Clinical Aspects of Peripheral Neuropathy

Leprous Neuropathy

Vasculitic Neuropathy

Dysproteinemic Neuropathies

Amyloid Neuropathy

Neuropathy Associated with Neoplasia

Neuropathy Associated with Endocrine and Metabolic Disease

Toxic Neuropathies

Genetically Determined Neuropathies

The Inflammatory Demyelinating Neuropathies

Idiopathic Inflammatory Neuropathies

Infectious Diseases Causing Neuropathy

Storage Diseases

Unclassified Neuropathies and Mimics

Peripheral nerve analysis is a challenging task for pathologists, given the advent of new diagnoses and techniques of analysis and the impact of molecular genetics. This book presents a simple, logical method for constructing a differential diagnosis based on pathology and clinical presentation. It also provides advice on the selection of ancillary molecular, immunohistochemical and genetic techniques to establish a definitive diagnosis. Clear, authoritative guidance is offered on diagnosis of the full range of neuropathies with the aid of a wealth of high-quality color photomicrographs and electron micrographs. The pathologist will benefit greatly from the identification of a variety of artifacts and normal structures occasionally encountered in nerve biopsies that need to be distinguished from specific pathologic alterations. This user-friendly, practical text will be an invaluable aid in achieving the most specific diagnosis possible.

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