Drug Discovery Toxicology From Target Assessment to Translational Biomarkers

By:

Yvonne Will

Contributor(s):

Material type: Text

TextPublication details: Hoboken, New Jersey John Wiley & Sons 2016Edition: illustratedDescription: 584 pagesISBN:

9781119053330
1119053331

Subject(s):

DDC classification:

615.9/02 23

LOC classification:

RA1238 (ebook) RA1238 .D75 2016 (print)

Summary: As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools • Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods • Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices

Item type: E-BOOKS

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Holdings
Item type	Current library	Collection	Status	Barcode
E-BOOKS	MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO	NFIC	2	EBS8586

Total holds: 0

As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process.

• Guides researchers as to what drug safety experiments are both practical and useful
• Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools
• Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods
• Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices

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