Sickle Cell Anemia From Basic Science to Clinical Practice.

By:

Fernando Ferreira Costa

Contributor(s):

Nicola Conran

Material type: Text

TextLanguage: English Publication details: London | Springer International Publishing Switzerland | 2016.Description: 439 Pages; Includes referencesISBN:

978-3-319-06712-4
978-3-319-06713-1 (eBook)

Subject(s):

-- Clinical biochemistry, Hematology, Internal medicine, Medical / Biochemistry, Medical / Clinical Medicine, Medical / General, Medical / Hematology, Medical / Internal Medicine, Medical sciences, Science / Life Sciences / Biochemistry, Medical / Research, Medicine, Medicine and Public Health, Sickle cell anemia

Online resources:

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Summary: Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated with the disease. Our knowledge regarding sickle cell disease mechanisms, while still not complete, has broadened considerably over the last decades. Sickle Cell Anemia: From Basic Science to Clinical Practice aims to provide an update on our current understanding of the disease’s pathophysiology and use this information as a basis to discuss its manifestations in childhood and adulthood. Current therapies and prospects for the development of new approaches for the management of the disease are also covered.

Item type: E-BOOKS

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Holdings
Item type	Current library	URL	Status	Barcode
E-BOOKS	MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO	Link to resource	Not for loan	20241028155346.0

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Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated with the disease. Our knowledge regarding sickle cell disease mechanisms, while still not complete, has broadened considerably over the last decades. Sickle Cell Anemia: From Basic Science to Clinical Practice aims to provide an update on our current understanding of the disease’s pathophysiology and use this information as a basis to discuss its manifestations in childhood and adulthood. Current therapies and prospects for the development of new approaches for the management of the disease are also covered.

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