Abstract:


"Background Childhood cancer possess a significant health challenge at Bugando Medical Centre (BMC) in Tanzania, with around 200 paediatric cancer cases diagnosed each year. Chemotherapy, vital for treatment, brings about chemotherapy-induced toxicities (CITs) and adverse drug reactions (ADRs), adding complexity to care. This study investigates parents and guardians perceptions and management of these ADRs in paediatric cancer treatment at BMC.

Methodology: The study at BMCs oncology department used a descriptive cross-sectional design with 200 parents/guardians. It assessed caregiver awareness, attitudes, and practices regarding chemotherapy ADRs through a semi structured questionnaire interview

Results and discussion: Approximately 80.5% of parents are aware of chemotherapy ADRs, yet theres a gap in effectively managing them. Around 69% demonstrate good practices, highlighting the need for educational interventions to enhance caregiver preparedness. Parental attitudes significantly influence monitoring and management practices, crucial for optimizing treatment outcomes

Conclusion: Top of Form Bottom of Form Improving parental awareness and practices regarding chemotherapy ADRs is crucial for enhancing paediatric oncology care at BMC. Recommendations include strengthening educational programs, promoting multidisciplinary collaboration, and expanding research initiatives to better support children undergoing chemotherapy, thereby advancing patient-centred care for paediatric cancer patients and their families."