Abstract:

Background: General and regional anaesthesia are the two main techniques used in caesarean section. Regional anaesthesia is preferred, but under certain circumstances, such as by patient request and in patients with back deformities, general anaesthesia is the only option. Commonly used induction agents include thiopental, ketamine, and propofol, depending on availability and the maternal clinical condition. The objective of this study was to investigate the effects of Ketamine and propofol on the neonatal Apgar score following emergency caesarean section in order to determine the superior agent for neonate outcome.

Methods: A hospital-based retrospective cohort study was employed, involving a sample of 104 neonates whose mother had caesarean section. Data were collected using checklist from medical record at Bugando Medical Centre that covered various aspects, including demographic information, weight, and type General anaesthetic used especially Propofol and ketamine and Apgar score. And analysed by using SPSS

Results: When identified type of anesthetic used, out of 104 patient, 61(58.7%) were delivered by using Ketamine and remaining 43(41%) neonates were delivered by caesarian section by using Propofol, A total 104 neonates had an Apgar score >7 at 5 minutes. Of those, 61 were in the Ketamine group and 43 in the Propofol group, degree of freedom of 4 with a p-value of 0.511 and degree of freedom of 4 with a p-value of 0.423 shows no association between neonates whose mother using propofol and ketamine

Conclusion: The choice between Propofol and Ketamine did not result in significant differences in the APGAR scores of neonates. This indicates that both anesthetic agents are comparable in terms of their immediate impact on neonatal outcomes in the context of cesarean sections.