Abstract:

Helicobacter pylori are well-recognized pathogen associated with chronic gastritis, peptic ulcer and an increased risk of gastric malignancies. Alcohol consumption has been suggested as a potential factor influencing the prevalence and severity of helicobacter pylori infection, through the relationship remains controversial. This study aimed to investigate the prevalence of helicobacter pylori infection among patients with history of chronic alcohol consumption.

Methods: A cross-sectional study was conducted among patients with a history of chronic alcohol consumption who attended at Haydom Lutheran hospital in mbulu-manyara, Tanzania and study was performed between April and August 2024. Data on alcohol intake, life factors and gastrointestinal symptoms were collected through standardized questionnaires. The diagnosis of Helicobacter pylori infection was done using rapid stool HpSA antigen test and data analysis was done using STATA Version 15.0

Results: The study included 401 chronic alcohol consumption patients with a medium age of 36[IQR: 17-99] years. A majority of study was male 213(53%), statistically significant were observed in social-demography among family number (p=0.02, p<0.05), and factor that has statistically significant associated with Helicobacter pylori infection status, types of alcohol (p=0.001, p< 0.05), unhand hygiene (p=0.017, p<0.05), mouth to mouth kissing (p=0.016, p<0.05).

Conclusion: Prevalence of helicobacter pylori infection among patients with a history of alcohol consumption was found to be 27.4% while alcohol consumption appears to significantly alter the prevalence of helicobacter pylori infection, it may contribute factor to increase risk of helicobacter pylori infection that create conducive environmental for helicobacter pylori colonization and persistence.