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Utility of Platelet Count in Predicting Upper Gastrointestinal Cancer in Patient with Dyspepsia at Bugando Medical Centre in Mwanza Tanzania.

By: Contributor(s): Material type: TextTextPublisher number: Wurzburg Road 35, Premises, Post Code: 33102 | P. O. Box 1464 Mwanza, Tanzania | Phone: (255) 28-298-3384 | Fax: (255) 28-298-3386 | Email: vc@bugando.ac.tz | Website: www.bugando.ac.tz Language: English Language: Kiswahili Publication details: Mwanza, Tanzania | Catholic University of Health and Allied Sciences [CUHAS-Bugando] | 2024. Description: 35 Pages; Includes ReferencesSubject(s): Summary: Abstract: Introduction: Dyspepsia is a common gastrointestinal (GI) disorder characterized by upper abdominal pain, discomfort, or fullness. The prevalence of dyspepsia in Tanzania is estimated to be between 15% and 25%. The causes of dyspepsia in Tanzania are not fully understood, but they are thought to include Helicobacter pylori infection, gastroesophageal reflux disease (GERD), and non-ulcer dyspepsia. The diagnosis of dyspepsia in Tanzania is usually made on clinical grounds. However, some patients may require further testing, such as an upper GI endoscopy, to rule out other conditions. Methodology: A case study involving 245 participants who attended Bugando Medical Centre for Gastrointestinal clinics in Mwanza, Tanzania was conducted from July 2024 to August 2024. Social demographics and other relevant information were collected using structured questionnaires that w used for data collection. Data were entered into the Microsoft excel sheet for clearing and coding then analyzed by using Stata version 1. Results: This study involved 245 patients with dyspeptic symptoms, out of which 121 (49.39%) had cancer and 5 (2.04%) had thrombocytosis (platelet count of >450,000). No statistical significant association observed in this study between platelet count and OGD findings (cancer). Conclusion: Further large-multi-center studies are recommended to make conclusion regarding platelet count as early biomarker of UGI malignancies.
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UNDERGRADUATE DISSERTATIONS MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO Not for loan 20240914134603.0
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Abstract:

Introduction: Dyspepsia is a common gastrointestinal (GI) disorder characterized by upper abdominal pain, discomfort, or fullness. The prevalence of dyspepsia in Tanzania is estimated to be between 15% and 25%. The causes of dyspepsia in Tanzania are not fully understood, but they are thought to include Helicobacter pylori infection, gastroesophageal reflux disease (GERD), and non-ulcer dyspepsia. The diagnosis of dyspepsia in Tanzania is usually made on clinical grounds. However, some patients may require further testing, such as an upper GI endoscopy, to rule out other conditions.

Methodology: A case study involving 245 participants who attended Bugando Medical Centre for Gastrointestinal clinics in Mwanza, Tanzania was conducted from July 2024 to August 2024. Social demographics and other relevant information were collected using structured questionnaires that w used for data collection. Data were entered into the Microsoft excel sheet for clearing and coding then analyzed by using Stata version 1.

Results: This study involved 245 patients with dyspeptic symptoms, out of which 121 (49.39%) had cancer and 5 (2.04%) had thrombocytosis (platelet count of >450,000). No statistical significant association observed in this study between platelet count and OGD findings (cancer).

Conclusion: Further large-multi-center studies are recommended to make conclusion regarding platelet count as early biomarker of UGI malignancies.

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