Susceptibility of Staphylococcus aureus to Antiseptics used at Bugando Medical Centre in Mwanza Tanzania
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TextPublisher number: Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tz Language: English Language: Kiswahili Publication details: Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] 27.04.2022 Description: Pages ix; 22; Includes Refferences and AppendicesSubject(s): Summary: ABSTRACT:
Introduction: Antiseptic is a substance that destroys or inhibits the growth of microorganisms such as bacteria especially in or on living tissue such as skin or mucous membranes .Antiseptics is used mainly for prevention of different infections. Resistance to antiseptics has shown to increase recently and this has led to spread of germs and development of infections (SSIs) which results to increased morbidity, hospital costs, treatment failure and death. This study determined the Susceptibility of Staphylococcus aureus to antiseptics used at Bugando Medical Centre in Mwanza Tanzania.
Methods: The susceptibility of 29 methicillin-resistant S. aureus (MRSA), 31 methicillin-sensitive S. aureus (MSSA) isolates from our hospital to three antiseptic agents which are 6% Hydrogen Peroxide (6% HP), 70% Methylated Spirit (70% MS) and 10% Povidone Iodine (10% PI) was determined by microtiter plate assay.
Results: The susceptibility of S.aureus strains increased based on the exposure time towards used antiseptics. The susceptibility was high in MSSA strains compared to MRSA strains on all used antiseptics at all different times of exposure.
Conclusion: From this study, increase in time of exposure of antiseptic was associated with high susceptibility rate for the tested bacterial isolates; this encourages increase in time of antiseptic exposure during skin decolonisation for better results.
| Item type | Current library | Collection | Copy number | Status | Barcode | |
|---|---|---|---|---|---|---|
| UNDERGRADUATE DISSERTATIONS | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | NFIC | CRECU/2261 | 1 | CRECU/2261 |
ABSTRACT:
Introduction: Antiseptic is a substance that destroys or inhibits the growth of microorganisms such as bacteria especially in or on living tissue such as skin or mucous membranes .Antiseptics is used mainly for prevention of different infections. Resistance to antiseptics has shown to increase recently and this has led to spread of germs and development of infections (SSIs) which results to increased morbidity, hospital costs, treatment failure and death. This study determined the Susceptibility of Staphylococcus aureus to antiseptics used at Bugando Medical Centre in Mwanza Tanzania.
Methods: The susceptibility of 29 methicillin-resistant S. aureus (MRSA), 31 methicillin-sensitive S. aureus (MSSA) isolates from our hospital to three antiseptic agents which are 6% Hydrogen Peroxide (6% HP), 70% Methylated Spirit (70% MS) and 10% Povidone Iodine (10% PI) was determined by microtiter plate assay.
Results: The susceptibility of S.aureus strains increased based on the exposure time towards used antiseptics. The susceptibility was high in MSSA strains compared to MRSA strains on all used antiseptics at all different times of exposure.
Conclusion: From this study, increase in time of exposure of antiseptic was associated with high susceptibility rate for the tested bacterial isolates; this encourages increase in time of antiseptic exposure during skin decolonisation for better results.
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