Abstract:

Background: The threat to human health posed by antibiotic resistance is of growing concern. Many commensal and pathogenic organisms have developed resistance to well established and newer antibiotics. The major selection pressure driving changes in the frequency of antibiotics available in the hospital stores. Hospital’s capacity to procure and distribute medicines and maintain a constant supply is affected by stock out. This study will provide the base from which further studies can be conducted on antibiotics use.

Methodology: The study was done at Misungwi District Hospital in Mwanza region, Tanzania. Invoices of purchased medicines for each month from June 2019 to May 2020 were checked and data for stock remains were taken from the bin card records, all data were recorded in the forms adapted from the manual entitled How to Investigate Drug Use in Health Facilities. Then to Microsoft excel version 2020 spread sheet for filtering. Data were transferred to Statistical Package for Social Sciences (SPSS) version 20 for further analysis.

Results: From June 2019 to May 2020, a total of 77,381,237Tsh were spent on medicines, of this amount, 19,838,650Tsh which is equivalent to 25.6% of the medicine’s budget spent on antimicrobials. Most common antibiotics includes amoxicillin, metronidazole and doxycycline. Amoxicillin expressed the highest DDD (1.942214) followed by Metronidazole (1.842652). Cefalexin is the antibiotic with the highest number of days out of stock which is 331 followed by Amoxiclavu 2114, Azithromycin 129, Ampiclox 122, Ceftriaxone 122 and other antibiotics such as.

Conclusion: The procurement of systemic antimicrobials at Misungwi District hospital lacks enough attention, this affects the procurement and consumption pattern of antimicrobials at Misungwi District Hospital.