Prescribing Patterns of Drugs Used for Peptic Ulcer Among Patients Admitted at Bugando Medical Centre, Mwanza Tanzania.
Material type:
Item type | Current library | Collection | Status | Barcode | |
---|---|---|---|---|---|
UNDERGRADUATE DISSERTATIONS | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | NFIC | 1 | UD0267 |
Abstract:
Background: Anti-secretory drugs are involved in the treatment of PUD. These include: Omeprazole, Lansoprazole, Rabeprazole Pantoprazole, Esomeprazole, Cimetidine and Ranitidine. Proton pump inhibitors with two antibiotics are involved in eradication of Helicobacter pylori infection within seven days of treatment (1).
Methods: A cross sectional retrospective study was conducted at BMC. Systematic random sampling was used to include 201 peptic ulcer patients. The data were analyzed with the aid of Statistical Package for Social Sciences window version 20.0. Descriptive statistics were generated for treatment patterns.
Results: Proton pump inhibitors (PPIs) in combination with antacids were the most prescribed drugs 103 (51.3%). The use of injectable PUD drugs was less frequent 4 (2.0%) than oral formulations 87 (43.3%). Generic drugs were more prescribed than proprietary name drugs 195 (97.0%) compared to 6 (3.0%) respectively). Prescriptions of H2 –receptor blockers combined with antacids were low 7 (3.5%). The average number of PUD drugs prescribed per prescription was (1.59±0.659).
Discussion: Medicines are essential tools in the management of diseases. Should be cost-effective, safe, efficacious and affordable, and the user must adhere to the dosage regimen.
Conclusion: Peptic ulcer disease treatment prescribing patterns were found be satisfactory. The most prescribed proton pump inhibitor for peptic ulcer was Rabeprazole. Generic prescribing was adequate. The average of drugs per prescription was satisfactory to standard treatment guidelines was not satisfactory.
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