Abstract:

Background: Urinary tract infection (UTI) is the most common disorder caused by bacterial agents in pregnancy, which can lead to important complications like abortion, intrauterine death and pyelonephritis in case of inappropriate diagnosis and treatment.

Objectives: to determine the prevalence and antimicrobial resistance profile among HIV negative pregnant women with UTI at BMC, Sekou Toure Hospital, Nyamagana district hospital and two selected health centers in Mwanza city, Tanzania.

Methods: This was a cross sectional study conducted from March to June 2016 at various health facilities in Mwanza city involving HIV negative pregnant women attending antenatal clinics. Mild-stream urine samples were collected from a total of 3000 pregnant women between the ages of 14 and 47 years. Samples were collected inside sterile disposable urine container from HIV negative pregnant. Data were computer and analyzed using STATA version 11 and p values ≤0.05 were considered to be statistically significant.

Results: Fifty-three (17.3%) of enrolled HIV negative pregnant women had significant bacteriuria. The prominent bacterial species isolated were Escherichia coli (30.2%) and Coagulase Negative Staphylococcus (28.3%). Majority of isolates were resistant to ampicillin and Contrimoxazole (83.5-100%).

Conclusions: The prevalence of bacteriuria among HIV negative pregnant women in this setting was 17.3%. The most isolated uropathogen in this setting was E. coli being resistant to ampicillin and Contrimoxazole. Ongoing antimicrobial resistance surveillance is recommended in our setting so as have rational treatment.