Abstract:

Background: chronic Rhinosinusits is a condition where cavities around passages (sinuses) become inflamed and swollen, thus interferes with drainage and causes mucus buildup for at least 3 months, it impacts negatively on quality of life that causing socioeconomic and academic loss. At BMC about 3% of patients attending ENT clinic in a week have presented with CRS, neverless, data on pathogens causing this clinical condition are still unknown.

Methods: this was a cross sectional study aimed to determine pattern of pathogens causing CRS among adult patients attending ENT clinic at BMC, conveniently selected from May to Jull 2018. Nasal meatus swab was taken from 48 adults patients attending ENT clinic at BMC presented with CRS, the transported into Stuart transport media to the laboratory within four hours. Swab sample was inoculated onto BA, MCA and SDA. BA and MCA were incubated at 37 degrees Celsius for 18-24 hours while SDA was incubated for at least 3 days, the interpreted based on clinical microbiology SOP. Antibacterial susceptibility test was done by Kirby Bauer diffusion method under CLSI guidelines.

Results: the gram positive bacteria were the most causative agent of CRS compared to the gram negative bacteria (13/19 vs.6/19, p=0.0116) of which the most isolated bacteria were s. aureus 13(68.42%) followed by E. coli and klebsiella oxytoca 2(10.53%) each. Aspergillus niger was the most fungi pathogen isolated from CRS patients. Most of isolated bacteria were 100% sensitive to ciprofloxacin, gentamycin and amikacin while resistant to ampicillin.

Conclusion: staphylococcus aureus and aspergillus niger were the prevalent isolated bacteria and fungi pathogens respectively, causing CRS among adult patients attending ENT clinic at BMC. Gentamycin and ciprofloxacin antibiotics were the drug of choice against bacteria species causing CRS to adult patients attending ENT clinic at BMC, Mwanza.