Toxoplasmic encephalitis with hyperpigmentation and pancytopenia after treatment with fansidar: a case report and review of literature

By:

RN Peck

Contributor(s):

Material type: Text

TextPublisher number: Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tz Language: English Series: ; Tanzania Medical Journal Volume 24 Issue 1Publication details: Mwanza, Tanzania: Tanzania Medical Journal & Catholic University of Health and Allied Sciences [CUHAS – Bugando] 2009 ISSN:

eISSN: 0856-0714

Online resources:

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Summary: Abstract: Toxoplasmic encephalitis is a common opportunistic infection in HIV infected individuals in sub-Saharan Africa but is difficult to treat in settings where first line therapy is not available. Fansidar has been recommended as an alternative regimen in these settings. In this report we describe the case of a patient with toxoplasmic encephalitis who was treated with fansidar with good response but fatal side effects. This case illustrates the potential dangers of treating toxoplasmic encephalitis with fansidar. Accordingly, we also review the literature regarding alternative treatment regimens for toxoplasmic encephalitis that may be equally effective but less toxic than fansidar.

Item type: RESEARCH ARTICLES

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Holdings
Item type	Current library	Collection	Copy number	Status	Barcode
RESEARCH ARTICLES	MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO	NFIC	RA1211	-1	RA1211

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Abstract:

Toxoplasmic encephalitis is a common opportunistic infection in HIV infected individuals in sub-Saharan Africa but is difficult to treat in settings where first line therapy is not available. Fansidar has been recommended as an alternative regimen in these settings. In this report we describe the case of a patient with toxoplasmic encephalitis who was treated with fansidar with good response but fatal side effects. This case illustrates the potential dangers of treating toxoplasmic encephalitis with fansidar. Accordingly, we also review the literature regarding alternative treatment regimens for toxoplasmic encephalitis that may be equally effective but less toxic than fansidar.

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