Immunology of hypertension in people with HIV
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TextPublisher number: Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tz Language: English Series: ; Journal of the American Heart Association Volume 9 Issue 4Publication details: Mwanza, Tanzania: Journal of the American Heart Association & Catholic University of Health and Allied Sciences [CUHAS – Bugando] 2020/2/18 Description: Pages e015725Online resources: Summary: HIV (PWH) are living longer and the leading causes of death in PWH are now cardiovascular disease (CVD), non-AIDS malignancies, and liver disease. 1 The risk of CVD in PWH is 2.5-fold higher than in HIV-uninfected adults, and HIV-associated CVD contributes to 2.6 million disability-associated life-years annually. 2
Hypertension is the leading risk factor for CVD in PWH. Globally, hypertension ranks as the strongest risk factor for CVD and causes> 10 million deaths and 200 million disability-adjusted life-years per year. 3 A recent meta-analysis indicates that the prevalence of hypertension in PWH on ART is 35% and increasing. 4 Data suggest that PWH and concurrent hypertension may experience an even higher risk of CVD than similar hypertensive HIV-negative adults. 5 Novel pathophysiologic mechanisms may drive hypertension in PWH. 6 HIV-specific mechanisms for hypertension may include microbial
| Item type | Current library | Collection | Copy number | Status | Barcode | |
|---|---|---|---|---|---|---|
| RESEARCH ARTICLES | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | NFIC | RA1161 | -1 | RA1161 |
HIV (PWH) are living longer and the leading causes of death in PWH are now cardiovascular disease (CVD), non-AIDS malignancies, and liver disease. 1 The risk of CVD in PWH is 2.5-fold higher than in HIV-uninfected adults, and HIV-associated CVD contributes to 2.6 million disability-associated life-years annually. 2
Hypertension is the leading risk factor for CVD in PWH. Globally, hypertension ranks as the strongest risk factor for CVD and causes> 10 million deaths and 200 million disability-adjusted life-years per year. 3 A recent meta-analysis indicates that the prevalence of hypertension in PWH on ART is 35% and increasing. 4 Data suggest that PWH and concurrent hypertension may experience an even higher risk of CVD than similar hypertensive HIV-negative adults. 5 Novel pathophysiologic mechanisms may drive hypertension in PWH. 6 HIV-specific mechanisms for hypertension may include microbial
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