Pathology of Female Cancers (Record no. 673)

MARC details
000 -LEADER
fixed length control field 04466nam a22001577a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-981-10-8605-2
International Standard Book Number 978-981-10-8606-9
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Takuya Moriya
9 (RLIN) 15482
245 ## - TITLE STATEMENT
Title Pathology of Female Cancers
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Kawasaki Medical School, Kurashiki, Japan
Name of publisher, distributor, etc. Springer Nature Singapore Pte Ltd.
Date of publication, distribution, etc. 2018
300 ## - PHYSICAL DESCRIPTION
Extent 211 Pages
520 ## - SUMMARY, ETC.
Summary, etc. Often, cancers are characterized by their abrupt occurrence. However, most<br/>cancers originate earlier and gradually develop in the subclinical stage.<br/>Even though this development varies from organ to organ, it may also differ<br/>for each patient. Hence, individualizing patients in terms of effective<br/>therapy and the early detection of cancer is imperative. Furthermore, the<br/>prevention of cancer is essential to avoid its proliferation.<br/>Surgical pathologists are expected to provide a definitive diagnosis of<br/>cancer and precisely assess the biological behavior of each patient.<br/>However, the accurate diagnosis of precancerous lesions and the precise<br/>assessment of the possibility and their progression rate into clinically<br/>significant cancer will be spectacular, rendering the precancerous stage as<br/>entirely curable.<br/>Apparently, the pathological diagnosis of all precancerous stages is<br/>complicated, as not all stages are morphologically evident. However, we<br/>may be able to detect precancerous “lesions.” On the basis of the organs<br/>and/or histological types, the concept and term of these lesions vary,<br/>including dysplasia (i.e., uterine cervix), atypical hyperplasia (i.e.,<br/>endometrium), adenoma (i.e., colorectum), intraepithelial neoplasia, or<br/>intraepithelial lesion. Occasionally, intraductal (noninvasive) carcinomas<br/>may also be included, as these are non-lethal and their distinction from<br/>dysplasia is complicated.<br/>The primary feature of precancerous lesions is their potential to<br/>progress into definite (invasive) cancer in future, even though the<br/>possibility and their progression rates vary, leading to the use of the terms<br/>“borderline lesions,” “borderline malignancy,” or “atypically proliferating<br/>lesions” in some organs (e.g., ovary). Although benign and malignant tumors<br/>may possess a middle degree of atypia, their biological behavior (early stage<br/>and the possibility of progression) may not be necessarily considered. At<br/>times, the same technical term may be used differently; for example,<br/>atypical hyperplasia in the breast signifies risk lesions rather than real<br/>precursors, and adenomas in various organs are entirely benign that will<br/>not progress into adenocarcinoma. Furthermore, several cancers may not<br/>have precursors and directly originate from healthy tissues (de novo<br/>cancer).<br/>This textbook intends to elucidate the current standards and novel<br/>knowledge regarding carcinogenesis, molecular features, histopathological
Expansion of summary note diagnosis, and the clinical significance of precancerous and early-stage<br/>female cancers such as breast, ovarian, and uterine carcinomas. Apparently,<br/>the pathways of cancer development significantly vary among organs, with<br/>heterogeneous precursors and early lesions based on the histological type<br/>of cancer in the same organ. Recently, several paradigm shifts have been<br/>advocated in these areas, for examples, the underlying mechanism of highgrade serous carcinoma of the ovary (and the peritoneum). It may be<br/>reckoned that the recognition of the current concept will lead to the most<br/>appropriate approach for the diagnosis, treatment, and patient care.<br/>As readers of this book may be familiar with the variegated development<br/>of these cancers, this book comprises eight chapters, including two chapters<br/>focusing on uterine cervical (precursors of squamous cell carcinoma and<br/>adenocarcinoma), one on endometrial (heterogeneity of precursors), three<br/>on ovarian (two pathways of carcinogenesis and the significance of<br/>borderline tumors), and two on mammary (significance of intrinsic subtype<br/>and risk assessment for non-cancerous lesions) cancers.<br/>All contributors to this book are exceptional Japanese surgical<br/>pathologists. Although each chapter in this book puts forth global<br/>perspectives, it also presents Japanese perspective in some parts. I hope<br/>that this book serves as a useful reference for grasping the advanced<br/>knowledge and facilitate the daily practice of pathologists, gynecologists,<br/>breast surgeons, and all medical staff members in these fields.
654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS
General subdivision Pathology
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type E-BOOKS
Holdings
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