Clinical immunology (Record no. 3606)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04784nam a22002057a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240305192238.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220103b |||||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780323044042 |
| International Standard Book Number | 0323044042 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CUHAS-BUGANDO |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | RKA, R. Robert |
| 9 (RLIN) | 27393 |
| 245 ## - TITLE STATEMENT | |
| Title | Clinical immunology |
| Remainder of title | principles and practice |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 3rd Edition |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | New York |
| Name of publisher, distributor, etc. | Mosby, Elsevier |
| Date of publication, distribution, etc. | 2008 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1578 pages |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In the 12 years since publication of the first edition of Clinical Immunology much has changed; as we have increasingly appreciated the nature<br/>of the molecular mechanisms underlying inflammatory responses to specific antigens, the discipline has surely become more complex, more<br/>interesting and more demanding of its practitioners. Acquired immunity, the specialized development of vertebrate host defenses, was for many<br/>decades the primary focus of attention. Recently, however, we have witnessed an explosion of information relating to the phylogenetically older<br/>systems of innate immunity, which has concurrently enlarged the purview of clinical immunology. In addition to those classical diseases of<br/>the acquired immune system, clinical immunologists today are increasingly interested in a range of inflammatory diseases where rearranged<br/>antigen-specific receptors have not been demonstrated or may not be involved. Rather than specific antigen receptors, these disorders are<br/>mediated by pathogen-recognition systems such as Toll-like receptors on NK lymphocytes and phagocytic cells. These trigger inflammatory<br/>effector processes that were later adopted by the acquired immune system, such as elaboration of soluble inflammatory mediators (cytokines<br/>and chemokines), complement activation, phagolysosome-mediated pathogen elimination and programmed cell death.<br/>The third edition reflects this improved understanding with increased attention to processes and diseases of inflammation and a broadly<br/>defined view of host defenses. We trust that this has been accomplished while retaining a principal focus on those many diseases at the core of<br/>clinical immunology arising from deficiency or aberration of functions of acquired immunity.<br/>Two changes will be immediately apparent to readers familiar with the previous editions. The third edition is, we believe, much enhanced<br/>by production in full color throughout. Clinical case photos are increased and are presented more usefully in the context of text discussion.<br/>Similarly line drawings are not only more attractive, but utilize color effectively to enrich their information content. The second obvious change<br/>is that we have chosen to publish the book in a single (albeit large) volume rather than in the previous two-volume format. We believe that<br/>by editing to reduce redundancy, judicious referencing (with an emphasis on recent reviews) and tightening presentation, the third edition is<br/>consequently more “user friendly,” eliminating the necessity to consult more than a single volume, while not compromising overall content<br/>quality or quantity. There is also a third important change that is not immediately obvious, but which will considerably enhance the long-term<br/>usefulness of the book. This third change is the intent to provide quarterly electronic updates to registered purchasers relating to key advances<br/>in clinical immunology since the publication of this edition. We are confident that such updates will help to keep the book fresh as our field<br/>advances.<br/>The process of editing a book of this size represents the combined efforts of many individuals in addition to the editors and authors. Two<br/>persons, however, warrant special thanks for their essential roles in shepherding this work to its conclusion: Martin Mellor and Randell Baker,<br/>whose efforts on behalf of the editors, authors and, finally, the readers, is gratefully acknowledged.<br/>We trust that the book continues to find a useful place on the desks and book shelves of clinical immunologists of many stripes—from the<br/>specialized practitioner of clinical immunology (either generalized or organ-system oriented), to the generalist or organ-based specialist who<br/>is interested in state-of-the-art approaches to management of inflammatory conditions, and to the fundamental immunologist interested |
| Expansion of summary note | mechanisms of immunologic diseases. Finally, upon reviewing this comprehensive text on clinical immunology, which delves into the many and<br/>increasingly diverse areas of immune system related diseases, the editors hope that this recording of the expanse and depth of knowledge in our<br/>specialty will impart a sense of pride and possession to those clinicians and researchers who call themselves clinical immunologists |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Clinical Immunology |
| 9 (RLIN) | 27381 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | E-BOOKS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 01/03/2022 | EBS8076 | 01/03/2022 | 01/03/2022 | E-BOOKS |