Escherichia coli, a Versatile Pathogen (Record no. 3310)
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000 -LEADER | |
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fixed length control field | 02170nam a22001817a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 211207b |||||||| |||| 00| 0 eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
International Standard Book Number | 9783319996646 |
International Standard Book Number | 3319996649 |
100 ## - MAIN ENTRY--PERSONAL NAME | |
Personal name | Gad Frankel |
9 (RLIN) | 26356 |
245 ## - TITLE STATEMENT | |
Title | Escherichia coli, a Versatile Pathogen |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Department of Life Sciences Imperial College London London, UK |
Name of publisher, distributor, etc. | Springer |
Date of publication, distribution, etc. | 2018 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 242 pages |
490 ## - SERIES STATEMENT | |
Volume/sequential designation | Volume 416 of Current Topics in Microbiology and Immunology |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Escherichia coli is a facultative anaerobic Gamma-proteobacterium, which belongs to the family Enterobacteriaceae. While being an important constituent of the normal gut microbiota, specialized E. coli clones have acquired genetic elements that allow them to compete with the endogenous commensals, colonise normally sterile niches and cause disease. E. coli pathotypes can cause intestinal and extra intestinal infections (e.g. UTI, sepsis) and associate with mammalian cells while being extra- or intra-cellular. In recent years, E. coli infections have become a serious clinical problem, due to the rapid spread of antibiotic resistance. Thus, infections with intestinal E. coli (e.g. E. coli O104) or extraintestinal pathogenic strains (e.g. E. coli ST131) are becoming difficult to treat and are often lethal. Consequently, there is a pressing need to develop alternative control measures, including the identification of new drug targets and development of vaccines that offer lasting protection.<br/><br/>This volume focuses on several types of E. coli infections (intestinal and extraintestinal), virulence factors, and E. coli pandemics. It addresses the problem of antibiotic resistance, and a dedicated chapter discusses the need to develop alternative control measures. Given its depth and breadth of coverage, the book will benefit all those interested in the biology, genetics, physiology and pathogenesis of E. coli, and in related vaccine development. |
654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
General subdivision | Science › Life Sciences › Bacteriology Medical / General Medical / Infectious Diseases Medical / Microbiology Science / Life Sciences / Bacteriology |
700 ## - ADDED ENTRY--PERSONAL NAME | |
9 (RLIN) | 26357 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | ddc |
Koha item type | E-BOOKS |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 12/07/2021 | EBS7775 | 12/07/2021 | 12/07/2021 | E-BOOKS |