Handbook on Immunosenescence (Record no. 3019)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02325nam a22002177a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211124b |||||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781402090639 |
| International Standard Book Number | 1402090633 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Tamas Fulop |
| 9 (RLIN) | 25654 |
| 245 ## - TITLE STATEMENT | |
| Title | Handbook on Immunosenescence |
| Remainder of title | basic understanding and clinical applications |
| Statement of responsibility, etc. | Biomedical and Life Sciences |
| 250 ## - EDITION STATEMENT | |
| Edition statement | illustrated |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Division of Geriatrics Research Center on Aging University of Sherbrooke Department of Medicine Sherbrooke, QC, Canada |
| Name of publisher, distributor, etc. | Springer Science & Business Media |
| Date of publication, distribution, etc. | 2009 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1693 pages |
| 490 ## - SERIES STATEMENT | |
| Series statement | SpringerLink: Springer |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | "Immunosenescence" is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. It represents a rapidly progressing science in the aging field, with a vertiginous volume of new data, knowledge and concepts concerning these changes. We are poised to be in a position to translate these accumulated data into the clinical setting via better understanding of the contribution of immunosenescence to age-associated pathologies, and their prevention by appropriate interventions. This authoritative handbook seeks to encompass the current state of our knowledge on the multitude of those changes to immunity related to aging, with contributions from experts in the research and clinical areas. This book therefore considers methods and models for studying immunosenescence; cellular immunosenescence of T cells, B cells, neutrophils, antigen presenting cells, NK, NKT and stem cells; genetics; mechanisms including receptors and signal transduction; mitochondria; proteasome; cytokines; neuro-endocrine-immune networks; inflammation; thymus; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; modulation by nutrition, lipids, vaccination and the question "can interventions to influence immunosenescence be realistically proposed based on our current state of knowledge?" |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| General subdivision | Medical › General Medical / General Medical / Geriatrics Medical / Immunology Medical / Research |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 25655 |
| 9 (RLIN) | 25656 |
| 9 (RLIN) | 25657 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | E-BOOKS |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 11/24/2021 | EBS7482 | 11/24/2021 | 11/24/2021 | E-BOOKS |