Glioma Signaling (Record no. 29523)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03395nam a22003017a 4500 |
| 001 - CONTROL NUMBER | |
| control field | 20241101110632.0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20241101111147.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 241101b |||||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 978-3-030-30650-2 |
| International Standard Book Number | 978-3-030-30651-9 (eBook) |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0065-2598 |
| International Standard Serial Number | 2214-8019 (electronic) |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | ddc |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Fuller form of name | Jolanta Barańska |
| 222 ## - KEY TITLE | |
| Key title | Abbracchio acid actin activation adenosine adenylate cyclase adhesion ADP Akt angiogenesis apoptosis arginine arginine deprivation astrocytes astrocytoma ATP Barańska binding Biol Chem brain tumors Burnstock Ca2+ calcium signaling cancer cells Cancer Res cannabinoid Cell Biol cell death cell invasion cell migration cell proliferation cofilin cytokine cytoskeleton differentiation effects EGFR endocannabinoid enzymes expression extracellular Fig function G GBM gene glioblastoma cells glioblastoma multiforme glioma C6 cells growth factor receptor GTPases H histone https://doi human glioblastoma increased induced inhibition inhibitor integrin interaction ligands malignant gliomas mechanisms mediated microglia modulation molecular motility mRNA myosin neurons Neurosci nucleotide nucleotide receptors overexpression P2X receptors P2Y1 receptor patients Pharmacol phosphorylation PI3K PI3K/Akt plasma membrane promotes protein kinase Purinergic Signal Rac1 rat regulation release response Rho role Sci serum signaling pathways Smad STAT STAT3 stem cells stimulation studies SWI/SNF target temozolomide therapeutic tissue transcription transforming growth tumor cells tyrosine kinase UTP vitro vivo Wang Zhang |
| 245 ## - TITLE STATEMENT | |
| Title | Glioma Signaling |
| 250 ## - EDITION STATEMENT | |
| Edition statement | Second Edition |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Biochemistry Nencki Institute of Experimental Biology Warsaw, Poland | |
| Name of publisher, distributor, etc. | Springer Nature Switzerland AG | |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 311 Pages |
| Extent | Includes References and Index |
| 490 ## - SERIES STATEMENT | |
| Series statement | Advances in Experimental Medicine and Biology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumor, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. This book is a reference on cellular signaling processes regulating gliomas physiology and invasiveness.<br/><br/>The work is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides and formation of complex signaling cascades induced by growth factors, cytokines and cannabinoids. The second edition of the book enriched in new chapters provides a framework explaining how signal transduction elements may modulate numerous genetic and epigenetic alterations, describes the role of local microenvironment in cellular growth, progression and invasion and, in the light of extensive new results, presents perspectives concerning potential targets for gliomas therapy. |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Cancer, Cytology, Medical / General, Medical / Oncology / General, Proteins, Science / Life Sciences / Biochemistry, Science / Life Sciences / Cell Biology, Science / Life Sciences / Molecular Biology, Cancer -- Research, Cell receptors, Cellular signal transduction, Gliomas. |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href=" https://doi.org/10.1007/978-3-030-30651-9 "> https://doi.org/10.1007/978-3-030-30651-9 </a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | E-BOOKS |
| Suppress in OPAC | |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Coded location qualifier | Total checkouts | Barcode | Date last seen | Copy number | Uniform resource identifier | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 11/01/2024 | S/OFFICE | 20241101110632.0 | 11/01/2024 | 20241101110632.0 | https://doi.org/10.1007/978-3-030-30651-9 | 11/01/2024 | E-BOOKS |