Inflammation and Metastasis (Record no. 29333)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02761nam a22002657a 4500 |
| 001 - CONTROL NUMBER | |
| control field | 20241025114206.0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20241025114624.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 241025b |||||||| |||| 00| 0 eng d |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER | |
| LC control number | 2016934318 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 978-4-431-56022-7 |
| International Standard Book Number | 978-4-431-56024-1 (eBook) |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | ddc |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.994 071 MAR |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Fuller form of name | Yoshiro Maru |
| 245 ## - TITLE STATEMENT | |
| Title | Inflammation and Metastasis |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Department of Pharmacology Tokyo Women’s Medical University Tokyo, Japan | |
| Name of publisher, distributor, etc. | Springer Japan | |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 515 Pages |
| Extent | Includes References and Index |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This book provides the latest information on cancer metastasis from the standpoint of inflammation, especially innate immune reactions caused by endogenous mediators but not exogenous pathogens, with ideas on how to understand the complicated mechanisms of metastasis as well as to interpret therapeutic targets. The book includes the topic of the emerging roles of endogenous TLR4 ligands whose functions are shared intriguingly by metastasis and auto-inflammatory diseases such as rheumatoid arthritis. For example, most cancer therapies established so far are effective initially. However, they eventually face the great obstacles of drug resistance, immune evasion, and metastatic progression. One of the endogenous TLR4 ligands is thought to contribute to all three processes. The most important features of the book are to explain a concept of homeostatic inflammation, disturbance of which in the lungs gives rise to the establishment of a pre-metastatic pulmonary microenvironment based on primary tumor-mediated hijacking of the innate immune defense system against respiratory infection. In addition, structure-based thinking is another important feature of this book. It is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, in the center of which cancer is located.<br/><br/>Given the proposal of precision medicine by President Obama in the United States in 2015 and the recent success of immune-modulator-based therapy, this book will appeal to researchers in a variety of fields with the title of the book connecting the worst disease (metastasis) and the most fundamental event (inflammation) that is common to many diseases. |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Cancer, Human physiology, Immunology, Medical / General, Medical / Immunology, Medical / Oncology / General, Medical / Physiology, Medical / Diseases, Science / Life Sciences / Human Anatomy & Physiology, Biomedicine, Cancer -- Molecular aspects -- Immunological aspects, Cancer -- Research, Inflammation, Medicine, Metastasis, Oncology. |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href=" DOI 10.1007/978-4-431-56024-1 "> DOI 10.1007/978-4-431-56024-1 </a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | E-BOOKS |
| Suppress in OPAC | |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total checkouts | Full call number | Barcode | Date last seen | Uniform resource identifier | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 10/25/2024 | 616.994 071 MAR | 20241025114206.0 | 10/25/2024 | DOI 10.1007/978-4-431-56024-1 | 10/25/2024 | E-BOOKS |