Liver Intra-arterial PRRT with 111In-Octreotide (Record no. 29330)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02780nam a22002537a 4500 |
| 001 - CONTROL NUMBER | |
| control field | 20241025104043.0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20241025104400.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 241025b |||||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 978-3-030-70772-9 |
| International Standard Book Number | 978-3-030-70773-6 (eBook) |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | ddc |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.994 LIM |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Fuller form of name | Georgios S. Limouris |
| 245 ## - TITLE STATEMENT | |
| Title | Liver Intra-arterial PRRT with 111In-Octreotide |
| Remainder of title | The Tumoricidal Efficacy of 111In Auger Electron Emission. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Nuclear Medicine Medical School National and Kapodistrian University of Athens Athens Greece | |
| Name of publisher, distributor, etc. | Springer Nature Switzerland AG | |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 265 Pages |
| Extent | Includes References |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This book describes in detail a clinical project that reveals the tumoricidal efficacy of Auger and internal conversion electrons, emitted from n.c.a. 111In and implemented in oncology as a treating armamentarium for peptide receptor radionuclide therapy (PRRT), targeting small size (ø ≤ 20 mm) tumors and micro-metastases.<br/><br/><br/>The keen interest in n.c.a. 111In began when it was observed that its Auger electron emission could be highly radiotoxic, due to its high LET when it decayed in the vicinity of cellular DNA. The somatostatin analog octreotide, labeled with [111In-diethylenetriaminepentaacetic acid (DTPA0-D-Phe1)] is an established diagnostic agent for the imaging of somatostatin receptor-positive neuro- (or non-neuro) endocrine tumors. It relies on receptor-mediated binding, internalization and installation in the lysosomes in the proximity of the nucleus; administered in large doses, loco-regionally, via the feeding artery of solid tumors, can be highly radiotoxic if they over-express somatostatin receptors, mainly of the sst2 histotype.<br/><br/>The book compares the results between i.v. and i.a. implementation in more than 80 patients after over 800 i.a. infusions in neuroendocrine tumors, meningiomas, paragangliomas and colorectal carcinomas in a single Institute (Aretaieion University Hospital) and encourages the i.a. way, leading to “tumor melting”, while minimizing the toxicity to healthy peritumoral liver tissue and critical organs (kidneys and bone marrow).<br/><br/>The volume is an invaluable tool for nuclear medicine physicians, interventional radiologists and oncologists dealing with radiopeptide therapies. |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Interventional radiology, Medical / Allied Health Services / Imaging Technologies, Medical / Clinical Medicine, Medical / Oncology / General, Medical / Radiology, Radiotherapy & Nuclear Medicine, Medical / Surgery / General, Nuclear medicine, Oncology, Surgery, Liver -- Cancer -- Radiotherapy. |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href=" https://doi.org/10.1007/978-3-030-70773-6 "> https://doi.org/10.1007/978-3-030-70773-6 </a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | E-BOOKS |
| Suppress in OPAC | |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total checkouts | Full call number | Barcode | Date last seen | Uniform resource identifier | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 10/25/2024 | 616.994 LIM | 20241025104043.0 | 10/25/2024 | https://doi.org/10.1007/978-3-030-70773-6 | 10/25/2024 | E-BOOKS |