Prevalence Of Acute Pancreatitis Among HIV Patients on Antiretroviral Drugs at Bugando Medical Centre in Mwanza, Tanzania. (Record no. 28947)

MARC details
000 -LEADER
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001 - CONTROL NUMBER
control field 20240926105628.0
003 - CONTROL NUMBER IDENTIFIER
control field 20240926105628.0
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240926110148.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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028 ## - PUBLISHER OR DISTRIBUTOR NUMBER
Source Wurzburg Road 35, Premises, Post Code: 33102 |
Source P. O. Box 1464 Mwanza, Tanzania |
Source Phone: (255) 28-298-3384 |
Source Fax: (255) 28-298-3386 |
Source Email: vc@bugando.ac.tz |
Source Website: www.bugando.ac.tz
040 ## - CATALOGING SOURCE
Transcribing agency ddc
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
Language code of text/sound track or separate title Kiswahili
100 ## - MAIN ENTRY--PERSONAL NAME
Relator term CUHAS/BM/1001250/T/21
Fuller form of name Meshack Munuo
245 ## - TITLE STATEMENT
Title Prevalence Of Acute Pancreatitis Among HIV Patients on Antiretroviral Drugs at Bugando Medical Centre in Mwanza, Tanzania.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania |
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS-Bugando] |
Date of publication, distribution, etc. 2024.
520 ## - SUMMARY, ETC.
Summary, etc. <br/><br/>Abstract:<br/><br/>Introduction: HIV infection and ART therapy are both toxic to the pancreas and may lead to both acute and chronic pancreatitis. Currently in Tanzania, there is no routine screening of pancreatic function in HIV patients attending at CTC clinic, despite being at a high risk of developing pancreatitis. This study aimed to determine the serum amylase and lipase levels among HIV patients attending CTC.<br/><br/>Methodology: A hospital based cross-sectional study that was conducted on 200 HIV patients on antiretroviral treatment from May to August 2024 at Bugando Medical Centre. Venous blood (4 mls) was collected in plain tube and separated to obtain serum by centrifugation. About 350µl of serum was used to determine the serum amylase and lipase levels using COBAS C111. Data were analyzed by STATA software version 15.<br/><br/>Result: A total of 200 HIV patients on ARV drugs were enrolled in this study. The mean age was 48.9 ± (11.8) years. Majority of the study participants were female 134/200 (67%). Among the 200 enrolled HIV patients on ARV drugs, 44% (88/200) had high levels of serum amylase and about 4% (8/200) had high level of serum lipase. The levels of serum amylase were significantly associated with female gender, P value = 0.001, whereas the serum lipase levels were significantly associated with alcohol consumption, P value =0.024. however, there was no significant association of high levels of serum amylase and lipase on the types of ARV drugs used, and cigarette smoking.<br/><br/>Conclusion and recommendation: High levels of serum amylase and lipase for pancreatic function are associated with female gender and alcohol consumption. There is need for routine screening for pancreatic enzymes profiles among HIV patients on ARV drug just as in other organs such as liver and kidney<br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Biochemistry & Molecular Biology
700 ## - ADDED ENTRY--PERSONAL NAME
Fuller form of name Bernard Charles Okamo
856 ## - ELECTRONIC LOCATION AND ACCESS
Public note Research Report Submitted in Partial Fulfillment for The Award of Bachelor of Medical Laboratory Sciences Degree of Catholic University of Health and Allied Sciences.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type UNDERGRADUATE DISSERTATIONS
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Holdings
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          MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO 09/26/2024   20240926105628.0 09/26/2024 09/26/2024 UNDERGRADUATE DISSERTATIONS
Catholic University of  Health and Allied Sciences - CUHAS
Directorate of ICT @ 2024