Prevalence and Associated Risk Factors for Liver Stiffness among Patients with Chronic Hepatitis B Infection Using Fibroscan at Bugando Medical Centre. (Record no. 28621)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02806nam a22003497a 4500 |
| 001 - CONTROL NUMBER | |
| control field | 20240903155935.0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | 20240903155935.0 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240913180900.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240903b |||||||| |||| 00| 0 eng d |
| 028 ## - PUBLISHER OR DISTRIBUTOR NUMBER | |
| Source | Wurzburg Road 35, Premises, Post Code: 33102 | |
| Source | P. O. Box 1464 Mwanza, Tanzania | |
| Source | Phone: (255) 28-298-3384 | |
| Source | Fax: (255) 28-298-3386 | |
| Source | Email: vc@bugando.ac.tz | |
| Source | Website: www.bugando.ac.tz. |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | ddc |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| Language code of text/sound track or separate title | Kiswahili |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Relator term | CUHAS/MD/4004029/T/19 |
| Fuller form of name | Luchagula K. Victory. |
| 245 ## - TITLE STATEMENT | |
| Title | Prevalence and Associated Risk Factors for Liver Stiffness among Patients with Chronic Hepatitis B Infection Using Fibroscan at Bugando Medical Centre. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania | |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS-Bugando] | |
| Date of publication, distribution, etc. | 2024. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 31 Pages |
| Extent | Includes References |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract:<br/><br/>Background: Chronic hepatitis B is a significant global health concern, and liver fibrosis is a common complication. This study aimed to determine the prevalence of liver stiffness in Tanzanian CHB patients and identify the associated risk factors.<br/><br/>Methods: A cross-sectional study of consecutive chronic hepatitis B patients performed VCTE and followed up at BMC Hospital, Mwanza, Tanzania, was conducted between 1 November, 2023, and 26 August, 2024. Liver fibrosis was defined as minimal (METAVIR F0-1) by LSM≤ 7.0 kPa and significant (METAVIR F2-4) by LSM ≥ 7.1 kPa. LSM assessments and medical records were retrospectively reviewed. The prevalence and determinants of significant liver fibrosis were analyzed.<br/><br/>Results: A total of 211 eligible patients were included; 143 patients (67.8%) were male. The mean age was 41.41 years (SD 10.92 years), and 57.3% had a body mass index ≥ 25 kg/m2. The prevalence of significant fibrosis (F2-4) were 44.1%. Significant determinants of significant fibrosis (F2-4) were male gender, advanced age and elevated liver biochemistries.<br/><br/>Conclusion: Approximately half of the Tanzanian patients with chronic viral hepatitis B had significant liver disease defined by Fibroscan, requiring further evaluation for specific treatment for hepatitis B virus. Determinants of significant liver fibrosis were male gender and high AST level.<br/> |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Internal Medicine |
| General subdivision | Biochemistry & Molecular Biology |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Fuller form of name | Semvua Bukheti Kilonzo |
| Fuller form of name | Hyasinta Michael Jaka |
| Fuller form of name | Felix Abdallah Tarimo |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Public note | Research Report Submitted for Partial Fulfillment of The Requirements for The Award of Bachelor of Doctor of Medicine at The Catholic University of Health and Allied Sciences. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | UNDERGRADUATE DISSERTATIONS |
| Suppress in OPAC | |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 09/03/2024 | 20240903155935.0 | 09/03/2024 | 09/03/2024 | UNDERGRADUATE DISSERTATIONS |