MARC details
000 -LEADER |
fixed length control field |
02493nam a22002777a 4500 |
001 - CONTROL NUMBER |
control field |
20240829102033.0 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
20240829102033.0 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20240829102409.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
240829b |||||||| |||| 00| 0 eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
978-1-4939-4021-9 |
|
International Standard Book Number |
978-1-4939-4023-3 (eBook) |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
1064-3745 |
|
International Standard Serial Number |
1940-6029 (electronic) |
040 ## - CATALOGING SOURCE |
Transcribing agency |
ddc |
041 ## - LANGUAGE CODE |
Language code of text/sound track or separate title |
English |
100 ## - MAIN ENTRY--PERSONAL NAME |
Fuller form of name |
Nicholas Hastie |
245 ## - TITLE STATEMENT |
Title |
The Wilms’ Tumor (WT1) Gene |
Remainder of title |
Methods and Protocols |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
New York : |
Name of publisher, distributor, etc. |
Springer Science+Business Media : |
Date of publication, distribution, etc. |
2016 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
247 Pages |
|
Extent |
Includes Index |
490 ## - SERIES STATEMENT |
Series statement |
Methods in Molecular Biology |
520 ## - SUMMARY, ETC. |
Summary, etc. |
This volume provides a thorough overview of the Wilms’ Tumour Gene (WT1). The book begins with three review chapters that cover the involvement of WT1 in pediatric cancer, kidney disease, and tissue development and homeostasis. The next few chapters discuss cell marking and lineage tracing, epicardial cell methodology, colony forming assays for bone marrow stem cells, angiogenesis assays and zebrafish tools. The next group of chapters explores the latest tools in genomics, molecular biology, and biochemistry. They discuss dissecting transcription factor function in cell free systems, ChiP seq, proteomics, RNA interactome, and multiphoton imaging of lipids, measuring the binding constants of protein-nucleic acid interactions, and bioinformatics approaches for analyzing Next Generation Sequence data. The final chapter discusses protocols for clinical trials for immune therapy using anti-WT1 peptides. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.<br/><br/>Practical and thorough, The Wilms’ Tumour (WT1) Gene: Methods and Protocols is a valuable resource for anyone who is interested in the diverse methodologies used in WT1 research. |
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME |
General subdivision |
Cancer, Medical / General, Medical / Genetics, Medical / Oncology / General, Medical genetics, Biomedicine, Cancer -- Research, Human genetics, Medicine, Nephroblastoma -- Laboratory manuals -- Genetic aspects, Nephroblastoma -- Pathogenesis -- Laboratory manuals -- Genetic aspects, Oncology. |
856 ## - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
<a href="DOI 10.1007/978-1-4939-4023-3 ">DOI 10.1007/978-1-4939-4023-3 </a> |
Link text |
DOI 10.1007/978-1-4939-4023-3 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
ddc |
Koha item type |
E-BOOKS |
Suppress in OPAC |
|