Metabolic syndrome among people living with HIV on antiretroviral therapy in Mwanza, Tanzania (Record no. 28082)

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000 -LEADER
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001 - CONTROL NUMBER
control field 20240612105227.0
003 - CONTROL NUMBER IDENTIFIER
control field 20240612105227.0
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240612110017.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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040 ## - CATALOGING SOURCE
Transcribing agency ddc
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
100 ## - MAIN ENTRY--PERSONAL NAME
Fuller form of name Evangelista Malindisa
245 ## - TITLE STATEMENT
Title Metabolic syndrome among people living with HIV on antiretroviral therapy in Mwanza, Tanzania
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mwanza, Tanzania :
Name of publisher, distributor, etc. Catholic University of Health and Allied Sciences [CUHAS-Bugando] :
Date of publication, distribution, etc. 2023
300 ## - PHYSICAL DESCRIPTION
Extent Pages 01-08
Extent Includes References
490 ## - SERIES STATEMENT
Volume/sequential designation BMC Endocr Disord . 2023 Apr 21;23(1):88. doi: 10.1186/s12902-023-01340-3.
520 ## - SUMMARY, ETC.
Summary, etc. Abstract :<br/><br/>Background: HIV and antiretroviral drugs, particularly protease inhibitors and nucleoside reverse transcriptase inhibitors, may increase the risk of Metabolic Syndrome (MetS) among people living with HIV (PLHIV). However, following the introduction of better drugs like dolutegravir, data on the burden of MetS are limited. This study aimed to assess the prevalence of MetS and associated factors among PLHIV on antiretroviral therapy (ART) in Tanzania.<br/><br/>Methods: This was a cross-sectional study among PLHIV aged ≥ 18 years on antiretroviral therapy for ≥ 1 year at Bugando Medical Centre in Mwanza conducted in 2020. Demographic and healthy-lifestyle-related non-communicable disease risk factors data were collected. Additionally, data on lipid profile, blood glucose, blood pressure, and waist circumference were collected for analysis of MetS according to the International Diabetes Federation criteria. Factors associated with MetS were assessed using logistic regression. A P ≤ 0.05 was considered statistically significant.<br/><br/>Results: Data for 223 participants were analyzed. The mean (SD) age was 44 (± 12) years and 79.8% (178) were females. A majority 78% (174) were on a tenofovir, lamivudine,and dolutegravir regimen. About 12.1% (27) were either current or past smokers, 45.3% (101) were past alcohol drinkers, 22.9% (51) were current drinkers, 12.1% (27) reported taking ≥ 5 servings of vegetables and fruits per day and 5.8% (13) were physically inactive. The prevalence of MetS was 22.9%. The only factors that were associated with Mets were fat mass index and adequate intake of vegetables and fruits, (adjusted odds ratio (aOR) 2.9, 95% CI 1.0, 7.9, P = 0.04) and (aOR1.2, 95% CI 1.0, 1.3, P = 0.02), respectively).<br/><br/>Conclusion: The prevalence of MetS remains high among PLHIV. Adiposity and adequate fruit and vegetable intake increased the risk. The introduction of new ART regimens shows no effect on MetS prevalence. Research is needed to understand how lifestyle changes could reduce MetS in PLHIV.<br/><br/>
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
General subdivision Antiretroviral therapy
General subdivision HIV
General subdivision MetS
700 ## - ADDED ENTRY--PERSONAL NAME
Fuller form of name Emmanuel Balandya
Fuller form of name Marina Njelekela
Fuller form of name Benson R Kidenya
Fuller form of name Filbert Francis
Fuller form of name Blandina T Mmbaga
Fuller form of name Haruna Dika
Fuller form of name Eligius Lyamuya
Fuller form of name Bruno Sunguya
Fuller form of name John Bartlett
Fuller form of name George PrayGod
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1186/s12902-023-01340-3">https://doi.org/10.1186/s12902-023-01340-3</a>
Link text https://doi.org/10.1186/s12902-023-01340-3
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme ddc
Koha item type RESEARCH ARTICLES
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          MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO 06/12/2024   20240612105227.0 06/12/2024 06/12/2024 RESEARCH ARTICLES
Catholic University of  Health and Allied Sciences - CUHAS
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