Predictors of 30-day mortality among patients with stroke admitted at a tertiary teaching hospital in Northwestern Tanzania (Record no. 28033)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03724nam a22004337a 4500 |
| 001 - CONTROL NUMBER | |
| control field | 20240610160814.0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | 20240610160814.0 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240610162024.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240610b |||||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | ddc |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Fuller form of name | Sarah Shali Matuja |
| 245 ## - TITLE STATEMENT | |
| Title | Predictors of 30-day mortality among patients with stroke admitted at a tertiary teaching hospital in Northwestern Tanzania |
| Remainder of title | A prospective cohort study |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mwanza, Tanzania : |
| Name of publisher, distributor, etc. | Catholic University of Health and Allied Sciences [CUHAS-Bugando] : |
| Date of publication, distribution, etc. | 2023 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | Pages 01-09 |
| Extent | Includes References |
| 490 ## - SERIES STATEMENT | |
| Volume/sequential designation | Front. Neurol. 13:1100477 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract : <br/><br/><br/>Background: Stroke is the second leading cause of death worldwide, with the highest mortality rates in low- to middle-income countries, particularly in sub-Saharan Africa. We aimed to investigate the predictors of 30-day mortality among patients with stroke admitted at a tertiary teaching hospital in Northwestern Tanzania.<br/><br/>Methods: This cohort study recruited patients with the World Health Organization's clinical definition of stroke. Data were collected on baseline characteristics, the degree of neurological impairment at admission (measured using the National Institutes of Health Stroke Scale), imaging and electrocardiogram (ECG) findings, and post-stroke complications. The modified Rankin scale (mRS) was used to assess stroke outcomes. Kaplan–Meier analysis was used to describe survival, and the Cox proportional hazards model was used to examine predictors of mortality.<br/><br/>Results: A total of 135 patients were enrolled, with a mean age of 64.5 years. Hypertension was observed in 76%, and 20% were on regular anti-hypertensive medications. The overall 30-day mortality rate was 37%. Comparing patients with hemorrhagic and ischemic stroke, 25% had died by day 5 [25th percentile survival time (in days): 5 (95% CI: 2–14)] versus day 23 [25th percentile survival time (in days): 23 (95% CI: 11–30) (log-rank p < 0.001)], respectively. Aspiration pneumonia was the most common medical complication, occurring in 41.3% of patients. ECG abnormalities were observed in 54.6 and 46.9% of patients with hemorrhagic and ischemic stroke, respectively. The most common patterns were as follows: ST changes 29.6 vs. 30.9%, T-wave inversion 34.1 vs. 38.3%, and U-waves 18.2 vs. 1.2% in hemorrhagic and ischemic stroke, respectively. Independent predictors for case mortality were as follows: mRS score at presentation (4–5) [aHR 5.50 (95% CI: 2.02–15.04)], aspiration pneumonia [aHR 3.69 (95% CI: 1.71–13.69)], ECG abnormalities [aHR 2.28 (95% CI: 1.86–5.86)], and baseline stroke severity [aHR 1.09 (95% CI: 1.02–1.17)].<br/><br/>Conclusion: Stroke is associated with a high 30-day mortality rate in Northwestern Tanzania. Concerted efforts are warranted in managing patients with stroke, with particular attention to individuals with severe strokes, ECG abnormalities, and swallowing difficulties to reduce early morbidity and mortality. |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| General subdivision | Stroke |
| General subdivision | Predictors |
| General subdivision | Morbidity |
| General subdivision | Mortality |
| General subdivision | Tanzania |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Fuller form of name | Gilbert Mlay |
| Fuller form of name | Fredrick Kalokola |
| Fuller form of name | Patrick Ngoya |
| Fuller form of name | Jemima Shindika |
| Fuller form of name | Lilian Andrew |
| Fuller form of name | Joshua Ngimbwa |
| Fuller form of name | Rashid Ali Ahmed |
| Fuller form of name | Basil Tumaini |
| Fuller form of name | Khuzeima Khanbhai |
| Fuller form of name | Reuben Mutagaywa |
| Fuller form of name | Mohamed Manji |
| Fuller form of name | Faheem Sheriff |
| Fuller form of name | Karim Mahawish |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.3389/fneur.2022.1100477">https://doi.org/10.3389/fneur.2022.1100477</a> |
| Link text | https://doi.org/10.3389/fneur.2022.1100477 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | ddc |
| Koha item type | RESEARCH ARTICLES |
| Suppress in OPAC | |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | 06/10/2024 | 20240610160814.0 | 06/10/2024 | 06/10/2024 | RESEARCH ARTICLES |